Delirium in the Elderly: A Comprehensive Review

被引:54
作者
Mittal, Vikrant [2 ]
Muralee, Sunanda [1 ]
Williamson, Deena [3 ]
McEnerney, Nicole [3 ]
Thomas, Jennifer [3 ]
Cash, Mary [3 ]
Tampi, Rajesh R. [1 ,3 ]
机构
[1] Yale Univ, Sch Med, Dept Psychiat, New Haven, CT 06511 USA
[2] BJC Healthcare Syst, Farmington, MO USA
[3] Masonicare, Wallingford, CT USA
来源
AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS | 2011年 / 26卷 / 02期
关键词
delirium; elderly; neurobiology; treatments; INTENSIVE-CARE-UNIT; PERSISTENT DELIRIUM; MULTICOMPONENT INTERVENTION; POSTOPERATIVE DELIRIUM; SUBSYNDROMAL DELIRIUM; GENETIC POLYMORPHISMS; PRECIPITATING FACTORS; MEDICAL INPATIENTS; PREVENT DELIRIUM; OLDER;
D O I
10.1177/1533317510397331
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Delirium is a common neuropsychiatric syndrome in the elderly characterized by concurrent impairments in cognition and behaviors. The etiologies for delirium are often multifactorial and are due to underlying medical illnesses and/or due to medication effect. The diagnosis of delirium is often missed in elderly patients and this condition may be mislabeled as depression or dementia. Untreated, delirium can have devastating consequences in the elderly with high rates of morbidity and mortality. Available evidence indicates that early detection, reduction of risk factors, and better management of this condition can decrease its morbidity rates. In this review, we discuss the etiology, neurobiology, diagnosis, prevention, and treatments for this potentially lethal condition in the elderly.
引用
收藏
页码:97 / 109
页数:13
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