Do STAT3 inhibitors have potential in the future for cancer therapy?

被引:193
作者
Wong, Andrea L. A. [1 ,2 ,3 ]
Hirpara, Jayshree L. [3 ]
Pervaiz, Shazib [4 ,5 ]
Eu, Jie-Qing [3 ]
Sethi, Gautam [6 ]
Goh, Boon-Cher [1 ,2 ,3 ,6 ]
机构
[1] Natl Univ Hlth Syst, Dept Haematol Oncol, Singapore, Singapore
[2] Natl Univ Hlth Syst, Natl Univ Canc Inst Singapore, Haematol Oncol Res Grp, Level 7,NUHS Tower Block,1E Kent Ridge Rd, Singapore 119228, Singapore
[3] Canc Sci Inst, Singapore, Singapore
[4] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Physiol, Singapore, Singapore
[5] Natl Univ Singapore, NUS Grad Sch Integrat Sci & Engn, Singapore, Singapore
[6] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Singapore, Singapore
基金
英国医学研究理事会;
关键词
GROWTH-FACTOR RECEPTOR; SIGNAL TRANSDUCER; DRUG-RESISTANCE; JAK INHIBITION; ACTIVATOR; TRANSCRIPTION-3; MUTATIONS; AZD1480; CELLS;
D O I
10.1080/13543784.2017.1351941
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:883 / 887
页数:5
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