Integrated functional nanocolloids covered with artificial cell membranes for biomedical applications

被引：90
作者：
Matsuno, Ryosuke [1 ,3 ,4 ]
Ishihara, Kazuhiko [1 ,2 ,3 ,4 ]
机构：
[1] Univ Tokyo, Dept Mat Engn, Bunkyo Ku, Tokyo 1138586, Japan
[2] Univ Tokyo, Sch Engn, Dept Bioengn, Bunkyo Ku, Tokyo 1138586, Japan
[3] Univ Tokyo, Ctr NanoBio Integrat, Bunkyo Ku, Tokyo 1138586, Japan
[4] Japan Sci & Technol Agcy, Core Res Evolut Sci & Technol CREST, Chiyoda Ku, Tokyo 1020075, Japan
来源：
NANO TODAY | 2011年 / 6卷 / 01期
关键词：
Nanocolloids; Artificial cell membrane; Surface modification; 2-Methacryloyloxyethyl phosphorylcholine (MPC) polymer; Protein adsorption; Cell adhesion; TRANSFER RADICAL POLYMERIZATION; BLOCK-COPOLYMER MICELLES; PHOSPHOLIPID POLYMER; QUANTUM-DOT; 2-METHACRYLOYLOXYETHYL PHOSPHORYLCHOLINE; GENE DELIVERY; DRUG-DELIVERY; BIOCOMPATIBLE POLYMER; SILICA NANOPARTICLES; SURFACE MODIFICATION;
D O I：
10.1016/j.nantod.2010.12.009
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The functionality of nanocolloids used in biomedical applications are subject to strong interference arising from significant interactions with biological components such as proteins and cells. Among the known examples of surface treatment of nanocolloids, the construction of an artificial cell membrane structure based on phospholipid polymers has proven effective in preventing the occurrence of biological reactions at the surface. Furthermore, certain bioactive molecules can be immobilized on the surface of the phospholipid polymer platform to generate bioaffinity for other biomolecules. This review describes preparation and characterization of integrated functional nanocolloids covered by artificial cell membrane structures and their performance in biomedical applications. (C) 2010 Elsevier Ltd. All rights reserved.
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收藏
页码：61 / 74
页数：14
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共 120 条
  • [1] Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy
    Aggarwal, Parag
    Hall, Jennifer B.
    McLeland, Christopher B.
    Dobrovolskaia, Marina A.
    McNeil, Scott E.
    [J]. ADVANCED DRUG DELIVERY REVIEWS, 2009, 61 (06) : 428 - 437
  • [2] Nanocrystal targeting in vivo
    Åkerman, ME
    Chan, WCW
    Laakkonen, P
    Bhatia, SN
    Ruoslahti, E
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (20) : 12617 - 12621
  • [3] Nano-engineering block copolymer aggregates for drug delivery
    Allen, C
    Maysinger, D
    Eisenberg, A
    [J]. COLLOIDS AND SURFACES B-BIOINTERFACES, 1999, 16 (1-4) : 3 - 27
  • [4] Functional one-dimensional lipid bilayers on carbon nanotube templates
    Artyukhin, AB
    Shestakov, A
    Harper, J
    Bakajin, O
    Stroeve, P
    Noy, A
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (20) : 7538 - 7542
  • [5] Colloidal dispersions of monodisperse magnetite nanoparticles modified with poly(ethylene glycol)
    Barrera, Carola
    Herrera, Adriana P.
    Rinaldi, Carlos
    [J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2009, 329 (01) : 107 - 113
  • [6] Synthesis of hydrophilic polymer-grafted ultrafine inorganic oxide particles in protic media at ambient temperature via atom transfer radical polymerization: use of an electrostatically adsorbed polyelectrolytic macroinitiator
    Chen, XY
    Armes, SP
    Greaves, SJ
    Watts, JF
    [J]. LANGMUIR, 2004, 20 (03) : 587 - 595
  • [7] Novel immunosuppressant agents targeting activated lymphocytes by biocompatible MPC polymer conjugated with interleukin-2
    Chiba, N.
    Ueda, M.
    Shimada, T.
    Jinno, H.
    Watanabe, J.
    Ishihara, K.
    Kitajima, M.
    [J]. EUROPEAN SURGICAL RESEARCH, 2007, 39 (02) : 103 - 110
  • [8] Development of gene vectors for pinpoint targeting to human hepatocytes by cationically modified polymer complexes
    Chiba, Naokazu
    Ueda, Masakazu
    Shimada, Toshiyuki
    Jinno, Hiromitsu
    Watanabe, Junji
    Ishihara, Kazuhiko
    Kitajima, Masaki
    [J]. EUROPEAN SURGICAL RESEARCH, 2007, 39 (01) : 23 - 34
  • [9] Living free-radical polymerization by reversible addition-fragmentation chain transfer: The RAFT process
    Chiefari, J
    Chong, YK
    Ercole, F
    Krstina, J
    Jeffery, J
    Le, TPT
    Mayadunne, RTA
    Meijs, GF
    Moad, CL
    Moad, G
    Rizzardo, E
    Thang, SH
    [J]. MACROMOLECULES, 1998, 31 (16) : 5559 - 5562
  • [10] Structural study of DNA condensation induced by novel phosphorylcholine-based copolymers for gene delivery and relevance to DNA protection
    Chim, YTA
    Lam, JKW
    Ma, Y
    Armes, SP
    Lewis, AL
    Roberts, CJ
    Stolnik, S
    Tendler, SJB
    Davies, MC
    [J]. LANGMUIR, 2005, 21 (08) : 3591 - 3598
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