Synthesis of Highly Substituted Fluoro Chromenones in a "One-Pot Four-Component Strategy" Using NFSI as a Fluorinating Reagent

被引：2

作者：

Reddy, Narra Srikanth ^{[1
]}

Swaroop, Desireddy Krishna ^{[1
]}

Kumar, Nagiri Ravi ^{[1
]}

Sreenivas, Avula ^{[1
]}

Narsaiah, Banda ^{[1
]}

机构：

[1] Indian Inst Chem Technol, CSIR, Fluoroorgan Div, Hyderabad 500007, India

来源：

CHEMISTRYSELECT | 2019年 / 4卷 / 47期

关键词：

Chromenones; Electrophilic fluorination; Fluoro imino chromenones; Hydroxy fluoro amino chromenone; Multicomponent reaction; CHEMISTRY; ACCESS;

D O I：

10.1002/slct.201904090

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient one pot four component strategy has been developed for the synthesis of highly substituted fluoro chromenone derivatives (5a-p) in good yields from beta-aryl thio acetanilide, aldehydes, cyclic 1,3-diketones and NFSI (N-Fluorobenzenesulfonimide) in presence of water. The fluoro imino chromenone intermediate 6 is isolated under the inert condition in high yield.

引用

页码：13768 / 13771

页数：4

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