PVA nanocomposite hydrogel loaded with silver nanoparticles enriched Nigella sativa oil

被引:6
作者
Sharmin, Eram [1 ]
Batubara, Afnan S. [1 ]
Tamboosi, Bushra Abdulrahman [1 ]
Al Khozay, Elaf Bander [1 ]
Alamoudi, Maha Khalid [1 ]
Al Aidaroos, Ohoud Zaki [1 ]
Albenayan, Jana Abdullaziz [1 ]
Lamfon, Majd Yousuf [1 ]
Sindi, Afnan Abdulhamaid Hassan [1 ]
Al-Madboly, Lamiaa A. [2 ]
Shoeib, Nagwa A. [3 ]
Alam, Manawwer [4 ]
机构
[1] Umm Al Qura Univ, Coll Pharm, Dept Pharmaceut Chem, Mecca 21955, Saudi Arabia
[2] Tanta Univ, Dept Pharmaceut Microbiol, Fac Pharm, Tanta, Egypt
[3] Tanta Univ, Dept Pharmacognosy, Fac Pharm, Tanta, Egypt
[4] King Saud Univ, Coll Sci, Dept Chem, Riyadh, Saudi Arabia
关键词
PVA; Nigella sativa; hydrogel; antibacterial; silver nanoparticles; ANTIBACTERIAL ACTIVITY; GREEN SYNTHESIS; BEHAVIOR; DRUG;
D O I
10.1080/24701556.2021.1963277
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Nigella sativa oil [NSO] was enriched with biosynthesized silver nanoparticles [NP] by simple, cost-effective, and less time-consuming "Green Chemistry" protocol. This combination [NSO/NP], on blending with PVA, produced transparent and foldable hydrogel film. The structure, morphology, hydrophilicity and thermal stability of hydrogel film confirmed the incorporation of inorganic NP in organic PVA matrix. FTIR spectrum of nanocomposite film revealed good interactions between PVA matrix, NP and NSO. SEM of PVA and NSO combination film exhibited lipidic NSO cloud-like phase (light grey) dispersed in PVA matrix (dark contrast), while in nanocomposite hydrogel film these lipidic clouds disappeared completely, and PVA matrix appeared donning a grey sheath. The nanocomposite film showed good folding endurance (> 300 folds) and antimicrobial behavior against Staphylococcus aureus (ATCC 25923), Enterococcus faecalis (ATTC 29212), Escherichia coli (ATCC 26922), Pseudomonas aeruginosa (ATCC 27853), Proteus mirabilis (ATCC 29906), Klebsiella pneumonia (MTCC109), Acinetobacter baumannii (NCTC 12156), and Candida albicans (ATCC90028) with prospective applications in antimicrobial packaging and wound dressings.
引用
收藏
页码:1134 / 1142
页数:9
相关论文
共 47 条
[1]   Biodegradable and Water Resistant Poly(vinyl) Alcohol (PVA)/Starch (ST)/Glycerol (GL)/Halloysite Nanotube (HNT) Nanocomposite Films for Sustainable Food Packaging [J].
Abdullah, Zainab Waheed ;
Dong, Yu .
FRONTIERS IN MATERIALS, 2019, 6
[2]   Synthesis and characterization of ZnO/PVA nanocomposites for antibacterial and electrochemical applications [J].
Abebe, Buzuayehu ;
Murthy, H. C. Ananda ;
Zereffa, Enyew Amare ;
Adimasu, Yeshaneh .
INORGANIC AND NANO-METAL CHEMISTRY, 2021, 51 (08) :1127-1138
[3]  
Ahmad Aftab, 2013, Asian Pacific Journal of Tropical Biomedicine, V3, P337, DOI 10.1016/S2221-1691(13)60075-1
[4]   Fabrication of antibacterial polyvinylalcohol nanocomposite mats with soluble starch coated silver nanoparticles [J].
Akturk, Aysen ;
Taygun, Melek Erol ;
Guler, Funda Karbancioglu ;
Goller, Gultekin ;
Kucukbayrak, Sadriye .
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2019, 562 :255-262
[5]   Dermatological effects of Nigella sativa [J].
Aljabre, Salih H. M. ;
Alakloby, Omar M. ;
Randhawa, Mohammad A. .
JOURNAL OF DERMATOLOGY DERMATOLOGIC SURGERY-JDDS, 2015, 19 (02) :92-98
[6]  
Allahverdiyev AM, 2011, EXPERT REV ANTI-INFE, V9, P1035, DOI [10.1586/eri.11.121, 10.1586/ERI.11.121]
[7]   Effect of different polyol-based plasticizers on thermal properties of polyvinyl alcohol:starch blends [J].
Aydin, Ahmet Alper ;
Ilberg, Vladimir .
CARBOHYDRATE POLYMERS, 2016, 136 :441-448
[8]   Multifunctional Hydrogel Nanocomposites for Biomedical Applications [J].
Barrett-Catton, Emma ;
Ross, Murial L. ;
Asuri, Prashanth .
POLYMERS, 2021, 13 (06)
[9]   Biomedical applications of hydrogels: A review of patents and commercial products [J].
Calo, Enrica ;
Khutoryanskiy, Vitaliy V. .
EUROPEAN POLYMER JOURNAL, 2015, 65 :252-267
[10]   Biodegradation behavior of starch-PVA films as affected by the incorporation of different antimicrobials [J].
Cano, Amalia I. ;
Chafer, Maite ;
Chiralt, Amparo ;
Gonzalez-Martinez, Chelo .
POLYMER DEGRADATION AND STABILITY, 2016, 132 :11-20