Mathematical modelling of enzymatic transesterification of mandelic acid with vinyl acetate

被引：0
作者：
Dabkowska, Katarzyna [1 ]
Szewczyk, Krzysztof W. [1 ]
机构：
[1] Warsaw Univ Technol, Fac Chem & Proc Engn, PL-00645 Warsaw, Poland
来源：
INZYNIERIA CHEMICZNA I PROCESOWA | 2007年 / 28卷 / 03期
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中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
Racemic mandelic acid was resolved by transesterification with vinyl acetate catalysed by Pseudomonas cepacia lipase. A high enantiomeric excess (>99%) of both unreacted substrate and acylated product was obtained at 25 degrees C using diisopropyl ether as the reaction medium. The Ping-Pong Bi-Bi mechanism and second order kinetics have been used to model the reaction rate. The best estimation has been obtained for the Ping-Pong Bi-Bi model without inhibition. Values of kinetic parameters were estimated.
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页码：795 / 802
页数：8
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