Translational regulation of the mRNA encoding the eukaryotic translation initiation factor 4E in Xenopus

被引:3
|
作者
Wakiyama, M [1 ]
Saigoh, M [1 ]
Ikeda, K [1 ]
Suzuki, A [1 ]
Miura, K [1 ]
机构
[1] Gakushuin Univ, Inst Biomol Sci, Toshima Ku, Tokyo 1718588, Japan
关键词
translational regulation; translation initiation factor 4E; Xenopus; oocytes;
D O I
10.1271/bbb.65.229
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We have cloned the cDNA for Xenopus eukaryotic translation initiation factor 4E (eIF4E), Here we show that translation of a luciferase mRNA that contains the 5' untranslated region derived from Xenopus erF4E is active in fertilized eggs, but is repressed in oocytes. The results suggest that the expression of Xenopus eIF4E is regulated at the translation level.
引用
收藏
页码:229 / 231
页数:3
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