Potassium Persulfate-Promoted N-Nitrosation of Secondary and Tertiary Amines with Nitromethane under Mild Conditions

被引：13

作者：

Azeez, Sadaf ^{[1
]}

Chaudhary, Priyanka ^{[1
]}

Sureshbabu, Popuri ^{[1
]}

Sabiah, Shahulhameed ^{[2
]}

Kandasamy, Jeyakumar ^{[1
]}

机构：

[1] Indian Inst Technol BHU, Dept Chem, Varanasi 221005, Uttar Pradesh, India

[2] Pondicherry Univ, Dept Chem, Pondicherry 605014, India

来源：

ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2018年 / 7卷 / 10期

关键词：

Potassium Persulfate; N-Nitrosation; Secondary amines; Nitromethane; Oxidation; C-H AZIDATION; EFFICIENT SYNTHESIS; NITROSAMINES; METAL; ACTIVATION; NITROSOANILINES; CHEMISTRY; K2S2O8; ARENES;

D O I：

10.1002/ajoc.201800437

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient route for the N-nitrosation of various secondary amines with nitromethane is described in the presence of potassium persulfate and DBU. Under optimized condition, tertiary amines underwent a dealkylative N-nitrosation with good yields. Inexpensive reagents, broad substrate scope and efficient conversion make the current protocol more attractive in organic synthesis.

引用

页码：2113 / 2119

页数：7

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