Pulmonary hypertension in the child with bronchopulmonary dysplasia

被引：28

作者：

Malloy, Kelsey W. ^{[1
]}

Austin, Eric D. ^{[1
]}

机构：

[1] Vanderbilt Univ, Med Ctr, Div Pediat Allergy Immunol & Pulm Med, Nashville, TN USA

来源：

PEDIATRIC PULMONOLOGY | 2021年 / 56卷 / 11期

关键词：

chronic lung disease; premature; pulmonary vascular disease; sildenafil; vasodilator; INHALED NITRIC-OXIDE; VASCULAR-DISEASE; PRETERM INFANTS; ARTERIAL-HYPERTENSION; NATRIURETIC PEPTIDE; CARDIAC-CATHETERIZATION; PREMATURE-INFANTS; LUNG-DISEASE; HOME OXYGEN; MANAGEMENT;

D O I：

10.1002/ppul.25602

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease of prematurity resulting from complex interactions of perinatal factors that often lead to prolonged respiratory support and increased pulmonary morbidity. There is also growing appreciation for the dysmorphic pulmonary bed characterized by vascular growth arrest and remodeling, resulting in pulmonary vascular disease and its most severe form, pulmonary hypertension (PH) in children with BPD. In this review, we comprehensively discuss the pathophysiology of PH in children with BPD, evaluate the current recommendations for screening and diagnosis of PH, discern associated comorbid conditions, and outline the current treatment options.

引用

页码：3546 / 3556

页数：11

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