Human babesiosis

被引:5
作者
Gorenflot, A [1 ]
Carcy, B [1 ]
Moubri, K [1 ]
Precigout, E [1 ]
Schetters, T [1 ]
机构
[1] Univ Montpellier 1, EA 2413, UFR Pharm, Biol Cellulaire & Mol Lab, F-34060 Montpellier 2, France
来源
MEDECINE ET MALADIES INFECTIEUSES | 1998年 / 28卷
关键词
Babesia; human babesiosis;
D O I
10.1016/S0399-077X(98)70223-9
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Hundreds of cases have been reported in the United States, but only 29 cases in Europe. The cattle parasite, B. divergens, was responsible for most cases in Europe; asplenic individuals were the highest risk group. In severe B. divergens infections, clinical manifestations were characterized by a severe intravascular haemolysis and the most efficient treatment consisted of a massive blood exchange transfusion and immediate subsequent chemotherapy by clindamycin. Mortality rate was high (42% of the splenectomized). In the United States, most cases were caused by the rodent parasite B. microti. Clinically human B. microti infection varied widely from an asymptomatic infection to a severe disease (mortality: 5%). Splenectomized, elderly, immunocompromised and HIV infected patients were predisposed to severe infection. The currently recommanded treatment of symptomatic cases was quinine plus clindamycin, A few other cases of human babesial infection have been described in China, Egypt, Mexico, South Africa and Taiwan.
引用
收藏
页码:363 / 366
页数:4
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