Unawareness of dyskinesias in Parkinson's and Huntington's diseases

被引：91

作者：

Vitale, C ^{[1
]}

Pellecchia, MT ^{[1
]}

Grossi, D ^{[1
]}

Fragassi, N ^{[1
]}

Cuomo, T ^{[1
]}

Di Maio, L ^{[1
]}

Barone, P ^{[1
]}

机构：

[1] Univ Naples Federico II, Dept Neurol Sci, Naples, Italy

来源：

NEUROLOGICAL SCIENCES | 2001年 / 22卷 / 01期

关键词：

D O I：

10.1007/s100720170066

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We performed a clinical study to evaluate the unawareness of dyskinesias in patients affected by Parkinson's disease (PD) and Huntington's disease (HD). Thirteen PD patients with levodopa-induced dyskinesias and 9 HD patients were enrolled. Patients were asked to evaluate the presence of dyskinesias while performing specific motor tasks. The Abnormal Involuntary Movement Scale (AIMS) and Goetz dyskinesia rating scale were administered to determine the severity of dyskinesias. The Unified Parkinson's disease rating scale (UPDRS) and Unified Huntington's Disease Rating Scale (UHDRS) were used in PD and HD patients, respectively. In PD we found a significant negative relation ship between unawareness score at standing and AIMS score and between unawareness score at hand pronation-supination and AIMS score for upper limbs. In HD we found a significant positive relationship between total unawareness score and UHDRS score and between total unawareness score and disease duration. In PD the unawareness seems to be inversely related with severity of dyskinesias, while in HD it is directly related to disease duration and severity.

引用

页码：105 / 106

页数：2

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