Differential expression of PD-1/PD-L1 axis and CD4/CD8 ratio in mediastinal lymph nodes of patients with idiopathic pulmonary fibrosis and lung cancer

被引:1
|
作者
Karampitsakos, Theodoros [1 ]
Chrysikos, Serafeim [2 ]
Vamvakaris, Ioannis [3 ]
Papaioannou, Ourania [1 ]
Bouros, Evangelos [4 ]
Tzilas, Vasilios [4 ]
Katsaras, Matthaios [1 ]
Dimakou, Katerina
Manali, Effrosyni [5 ]
Papiris, Spyridon [5 ]
Bouros, Demosthenes [4 ]
Bakakos, Petros [4 ]
Tzouvelekis, Argyris [1 ]
机构
[1] Univ Hosp Patras, Dept Resp Med, Patras, Greece
[2] SOTIRIA, Hosp Thorac Dis, Dept Pneumonol 5, Athens, Greece
[3] SOTIRIA, Hosp Thorac Dis, Dept Pathol, Athens, Greece
[4] Natl & Kapodistrian Univ Athens, Sch Med, Hosp Thorac Dis, Acad Dept Pneumonol 1, Athens, Greece
[5] Natl & Kapodistrian Univ Athens, ATTIKON Univ Hosp, Athens Med Sch, Pulm Med Dept 2, Athens, Greece
关键词
Immunology; Bronchoscopy; Idiopathic pulmonary fibrosis;
D O I
10.1183/13993003.congress-2021.PA387
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
PA387
引用
收藏
页数:2
相关论文
共 50 条
  • [11] Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway
    Haspot, Fabienne
    Fehr, Thomas
    Gibbons, Carrie
    Zhao, Guiling
    Hogan, Timothy
    Honjo, Tasuku
    Freeman, Gordon J.
    Sykes, Megan
    BLOOD, 2008, 112 (05) : 2149 - 2155
  • [12] The role of PD-1/PD-L1 axis in idiopathic pulmonary fibrosis: Friend or foe?
    Jiang, Aimin
    Liu, Na
    Wang, Jingjing
    Zheng, Xiaoqiang
    Ren, Mengdi
    Zhang, Wei
    Yao, Yu
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [13] Infiltration of CD8 T Cells and Expression of PD-1 and PD-L1 in Synovial Sarcoma
    Nowicki, Theodore S.
    Akiyama, Ryan
    Huang, Rong Rong
    Shintaku, I. Peter
    Wang, Xiaoyan
    Tumeh, Paul C.
    Singh, Arun
    Chmielowski, Bartosz
    Denny, Christopher
    Federman, Noah
    Ribas, Antoni
    CANCER IMMUNOLOGY RESEARCH, 2017, 5 (02) : 118 - 126
  • [14] PD-1/PD-L1 Axis in Lung Cancer
    Santini, Fernando C.
    Hellmann, Matthew D.
    CANCER JOURNAL, 2018, 24 (01): : 15 - 19
  • [15] Comparative expression analysis of PD-1, PD-L1, and CD8A in lung adenocarcinoma
    Ma, Ke
    Qiao, Yulei
    Wang, Hao
    Wang, Shuai
    ANNALS OF TRANSLATIONAL MEDICINE, 2020, 8 (22)
  • [16] Systemic CD4 Immunity and PD-L1/PD-1 Blockade Immunotherapy
    Escors, David
    Bocanegra, Ana
    Chocarro, Luisa
    Blanco, Ester
    Pineiro-Hermida, Sergio
    Garnica, Maider
    Fernandez-Rubio, Leticia
    Vera, Ruth
    Arasanz, Hugo
    Kochan, Grazyna
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (21)
  • [17] Prognostic impact of PD-1, PD-L1, and CD8 genes expression in peripheral blood in gastric cancer.
    Ito, Shuhei
    Masuda, Takaaki
    Fukagawa, Takeo
    Kouyama, Yuta
    Wakiyama, Hiroaki
    Yoshikawa, Yukihiro
    Noda, Miwa
    Kidogami, Shinya
    Hu, Qingjiang
    Sato, Kuniaki
    Nambara, Sho
    Saito, Tomoko
    Sakimura, Shotaro
    Hayashi, Naoki
    Kuroda, Yousuke
    Eguchi, Hidetoshi
    Sasako, Mitsuru
    Mimori, Koshi
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35
  • [18] PD-L1 expression in patients with idiopathic pulmonary fibrosis
    Kronborg-White, Sissel
    Madsen, Line Bille
    Bendstrup, Elisabeth
    Poletti, Venerino
    EUROPEAN RESPIRATORY JOURNAL, 2021, 58
  • [19] PD-L1 Expression in Patients with Idiopathic Pulmonary Fibrosis
    Kronborg-White, Sissel
    Madsen, Line Bille
    Bendstrup, Elisabeth
    Poletti, Venerino
    JOURNAL OF CLINICAL MEDICINE, 2021, 10 (23)
  • [20] Characterizing cancers by prevalence on the PD-L1/CD8 axis
    Schmidt, Guenter
    Steele, Keith
    Meier, Armin
    Herz, Thomas
    Tan, Tze Heng
    Higgs, Brandon
    Althammer, Sonja
    Huss, Ralf
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2017, 5