Silphos [PCl3-n(SiO2)n]:: a heterogeneous phosphine reagent for formylation and acetylation of alcohols and amines with ethyl formate and acetate

被引：67

作者：

Iranpoor, N ^{[1
]}

Firouzabadi, H ^{[1
]}

Jamalian, A ^{[1
]}

机构：

[1] Shiraz Univ, Coll Sci, Dept Chem, Shiraz 71454, Iran

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 46期

关键词：

silphos; formylation; acetylation; alcohol; amine; ethyl formate; ethyl acetate; formate; acetate;

D O I：

10.1016/j.tetlet.2005.09.078

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alcohols and amines are formylated and acetylated in the presence of Silphos [PCl3-n(SiO2)(n)] in ethyl formate and ethyl acetate in high to excellent yields. This procedure provides a method to separate the product by a simple filtration. (c) 2005 Published by Elsevier Ltd.

引用

页码：7963 / 7966

页数：4

共 51 条

[1]

[Anonymous], 2003, CRC Handbook of Chemistry and Physics, V84th

[2]

BARLUENGA J, 1985, SYNTHESIS-STUTTGART, P426

[3] Zn(ClO4)2•6H2O as a powerful catalyst for a practical acylation of alcohols with acid anhydrides [J].