Automated calculation of the distal contractile integral in esophageal pressure topography with a region-growing algorithm

被引:13
作者
Lin, Z. [1 ]
Roman, S. [1 ]
Pandolfino, J. E. [1 ]
Kahrilas, P. J. [1 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Dept Med, Chicago, IL 60611 USA
关键词
biomedical signal processing; distal contractile integral; esophageal manometry; esophageal pressure topography; region-growing; HIGH-RESOLUTION MANOMETRY; MOTILITY;
D O I
10.1111/j.1365-2982.2011.01795.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background The distal contractile integral (DCI) is an index of contractile vigor in high-resolution esophageal pressure topography (EPT) calculated as the product of amplitude, duration, and span of the distal esophageal contraction. The aim of this study was to develop an automated algorithm calculating DCI. Methods The DCI was calculated conventionally using ManoView (TM) (Given Imaging, Los Angeles, CA, USA) software in EPT studies from 72 controls and 20 patients and compared to the calculation using a MATLAB (TM) (Version 7.9.0, R2009b; The MathWorks Inc., Natick, MA, USA) 'region-growing' algorithm. This algorithm first established the spatial limits of the distal contraction (the proximal pressure trough to either the distal pressure trough or to the superior margin of the lower esophageal sphincter at rest). Pixel-by-pixel horizontal line segments were then analyzed within this span starting at the pressure maximum and extending outward from that point. The limits of 'region-growing' were defined either by the spatial DCI limits or by encountering a pressure <20 mmHg. The DCI was then calculated as the total units of mmHg s cm greater than 20 mmHg within this domain. Key Results Excellent correlation existed between the two methods (r = 0.98, P < 0.001). The DCI values obtained with the conventional calculation were slightly but significantly greater than with the region-growing algorithm. Differences were attributed to the inclusion of vascular pressures in the conventional calculation or to differences in localization of the distal limit of the DCI. Conclusions & Inferences The proposed region-growing algorithm provides an automated method to calculate DCI that limits inclusion of vascular pressure artifacts and minimizes the need for user input in data analysis.
引用
收藏
页码:E4 / E10
页数:7
相关论文
共 14 条
[1]   Cardiovascular compression of the esophagus and spread of gastro-esophageal reflux [J].
Babaei, A. ;
Mittal, R. K. .
NEUROGASTROENTEROLOGY AND MOTILITY, 2011, 23 (01) :45-E3
[2]   TOPOGRAPHY OF THE ESOPHAGEAL PERISTALTIC PRESSURE WAVE [J].
CLOUSE, RE ;
STAIANO, A .
AMERICAN JOURNAL OF PHYSIOLOGY, 1991, 261 (04) :G677-G684
[3]   Quantifying esophageal peristalsis with high-resolution manometry: a study of 75 asymptomatic volunteers [J].
Ghosh, SK ;
Pandolfino, JE ;
Zhang, Q ;
Jarosz, A ;
Shah, N ;
Kahrilas, PJ .
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2006, 290 (05) :G988-G997
[4]   Physiology of the esophageal pressure transition zone: separate contraction waves above and below [J].
Ghosh, SK ;
Janiak, P ;
Schwizer, W ;
Hebbard, GS ;
Brasseur, JG .
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2006, 290 (03) :G568-G576
[5]   Region growing: A new approach [J].
Hojjatoleslami, SA ;
Kittler, J .
IEEE TRANSACTIONS ON IMAGE PROCESSING, 1998, 7 (07) :1079-1084
[6]  
Liang HL, 2004, P ANN INT IEEE EMBS, V26, P620
[7]  
Lin ZY, 2010, GASTROENTEROLOGY, V138, pS465
[8]   A New Approach to Analysis and Modeling of Esophageal Manometry Data in Humans [J].
Najmabadi, Mani ;
Devabhaktuni, Vijay K. ;
Sawan, Mohamad ;
Mayrand, Serge ;
Fallone, Carlo A. .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 2009, 56 (07) :1821-1830
[9]   High-resolution manometry in clinical practice: utilizing pressure topography to classify oesophageal motility abnormalities [J].
Pandolfino, J. E. ;
Fox, M. R. ;
Bredenoord, A. J. ;
Kahrilas, P. J. .
NEUROGASTROENTEROLOGY AND MOTILITY, 2009, 21 (08) :796-806
[10]   Classifying esophageal motility by pressure topography characteristics: A study of 400 patients and 75 controls [J].
Pandolfino, John E. ;
Ghosh, Sudip K. ;
Rice, John ;
Clarke, John O. ;
Kwiatek, Monika A. ;
Kahrilas, Peter J. .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2008, 103 (01) :27-37