Recent progress in SERS biosensing

被引:507
作者
Bantz, Kyle C. [2 ]
Meyer, Audrey F. [2 ]
Wittenberg, Nathan J. [1 ]
Im, Hyungsoon [1 ]
Kurtulus, Ozge [2 ]
Lee, Si Hoon [3 ]
Lindquist, Nathan C. [1 ]
Oh, Sang-Hyun [1 ,3 ]
Haynes, Christy L. [2 ]
机构
[1] Univ Minnesota, Dept Elect & Comp Engn, St Paul, MN USA
[2] Univ Minnesota, Dept Chem, St Paul, MN USA
[3] Univ Minnesota, Dept Biomed Engn, St Paul, MN USA
关键词
SURFACE-ENHANCED-RAMAN; HIGHLY SENSITIVE DETECTION; RAPID DETECTION; IN-VIVO; ANTHRAX BIOMARKER; NANOSPHERE LITHOGRAPHY; SCATTERING DETECTION; GOLD NANOPARTICLES; SPECTROSCOPY SERS; AMINO-ACIDS;
D O I
10.1039/c0cp01841d
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
This perspective gives an overview of recent developments in surface-enhanced Raman scattering (SERS) for biosensing. We focus this review on SERS papers published in the last 10 years and to specific applications of detecting biological analytes. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids, lipids, peptides, and proteins, as well as for in vivo and cellular sensing. Current SERS substrate technologies along with a series of advancements in surface chemistry, sample preparation, intrinsic/extrinsic signal transduction schemes, and tip-enhanced Raman spectroscopy are discussed. The progress covered herein shows great promise for widespread adoption of SERS biosensing.
引用
收藏
页码:11551 / 11567
页数:17
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