Idesolide:: A new spiro compound from Idesia polycarpa

被引：37

作者：

Kim, SH

Sung, SH

Choi, SY

Chung, YK

Kim, J

Kim, YC

机构：

[1] Seoul Natl Univ, Coll Pharm, Seoul 151742, South Korea

[2] Elcom Sci Co Ltd, Inst Life Sci, Seoul 152848, South Korea

[3] Seoul Natl Univ, Dept Chem, Seoul 151742, South Korea

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 15期

关键词：

D O I：

10.1021/ol051105f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Idesolide, a new spiro compound possessing tetrahydrobenzodioxole structure, was isolated from the fruits of Idesia polycarpa Maxim. Its structure was established by NMR and MS spectroscopic analysis with single-crystal X-ray experiments. Idesolide significantly reduced nitric oxide production induced by lipopolysaccharide in BV2 microglial cells.

引用

页码：3275 / 3277

页数：3

共 8 条

[1] Phenyl beta-D-glucopyranoside derivatives from the fruits of Idesia polycarpa [J].

Chou, CJ ;

Lin, LC ;

Tsai, WJ ;

Hsu, SY ;

Ho, LK .

JOURNAL OF NATURAL PRODUCTS, 1997, 60 (04) :375-377

[2] A PHYTOCHEMICAL INVESTIGATION OF HOMALIUM-CEYLANICUM [J].

EKABO, OA ;

FARNSWORTH, NR ;

SANTISUK, T ;

REUTRAKUL, V .

JOURNAL OF NATURAL PRODUCTS, 1993, 56 (05) :699-707

[3]

IUPAC, 1979, NOM ORG CHEM

[4]

KIM TW, 1996, WOODY PLANTS KOREA, P126

[5]

Mori A, 2001, LIQ CRYST, V28, P1425, DOI 10.1080/0267890110067245

[6] Differential regulation of inducible nitric oxide synthase and cytokine gene expression by forskolin and dibutyryl-cAMP in lipopolysaccharide-stimulated murine BV2 microglial cells [J].

Woo, MS ;

Jung, SH ;

Hyun, JW ;

Kim, HS .

NEUROSCIENCE LETTERS, 2004, 356 (03) :187-190

[7]

ZHOU Y, 2003, TIANRAN CHANWU YANJI, V15, P13

[8]

Zhou Y., 2003, TIANRAN CHANWU YANJI, V15, P17

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