Nutritional risk index as a predictor of mortality in acutely decompensated heart failure

被引：14

作者：

Cho, Jae Yeong ^{[1
]}

Kim, Kye Hun ^{[1
]}

Cho, Hyun-Jai ^{[2
]}

Lee, Hae-Young ^{[2
]}

Choi, Jin-Oh ^{[3
]}

Jeon, Eun-Seok ^{[3
]}

Lee, Sang Eun ^{[4
]}

Kim, Min-Seok ^{[4
]}

Kim, Jae-Joong ^{[4
]}

Hwang, Kyung-Kuk ^{[5
]}

Chae, Shung Chull ^{[6
]}

Baek, Sang Hong ^{[7
]}

Kang, Seok-Min ^{[8
]}

Choi, Dong-Ju ^{[9
]}

Yoo, Byung-Su ^{[10
]}

Ahn, Youngkeun ^{[1
]}

Park, Hyun-Young ^{[11
]}

Cho, Myeong-Chan ^{[4
]}

Oh, Byung-Hee ^{[2
]}

机构：

[1] Chonnam Natl Univ Hosp, Dept Cardiovasc Med, Gwangju, South Korea

[2] Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea

[3] Sungkyunkwan Univ, Coll Med, Seoul, South Korea

[4] Univ Ulsan, Coll Med, Seoul, South Korea

[5] Chungbuk Natl Univ, Coll Med, Cheongju, South Korea

[6] Kyungpook Natl Univ, Coll Med, Daegu, South Korea

[7] Catholic Univ Korea, Seoul, South Korea

[8] Yonsei Univ, Coll Med, Seoul, South Korea

[9] Seoul Natl Univ, Bundang Hosp, Seongnam, South Korea

[10] Yonsei Univ, Wonju Coll Med, Wonju, South Korea

[11] NIH, Osong, South Korea

来源：

PLOS ONE | 2018年 / 13卷 / 12期

关键词：

BODY-MASS INDEX; VENTRICULAR DIASTOLIC FUNCTION; CARDIOVASCULAR-DISEASE; CATABOLIC/ANABOLIC IMBALANCE; EXERCISE; ALBUMIN; IMPACT; MEN;

D O I：

10.1371/journal.pone.0209088

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Background We investigated the role of nutritional risk index (NRI) in predicting 1-year mortality in patients with acute decompensated heart failure (ADHF). Methods Among 5,625 cohort patients enrolled in Korean Acute Heart Failure (KorAHF) Registry, a total of 5,265 patients who were possible to calculate NRI [NRI = (1.519 x serum albumin [g/dl]) + (41.7 x weight [kg]/ideal body weight [kg])] were enrolled. The patients were divided into 4 groups according to the NRI quartile; Q1 <89 (n = 1121, 69.9 +/- 14.5 years, 632 males), Q2 89-95 (n = 1234, 69.7 +/- 14.4 years, 677 males), Q3 95-100 (n = 1199, 68.8 +/- 14.0 years, 849 males), Q4>100 (n = 1711, 65.6 +/- 14.5 years, 779 males). Primary end-point was all-cause mortality at 1-year clinical follow-up. Results The 1-year mortality was significantly increased as the NRI quartile decreased, and the lowest NRI quartile was associated with the highest 1-year mortality (Q1: 27.5% vs. Q2: 20.9% vs. Q3: 12.9% vs. Q4: 8.7%, linear p <0.001). On Kaplan-Meier survival analysis, the significant inter-quartile difference was observed (p <0.001 for all). In multivariate analysis using Cox proportional hazard regression, the lowest NRI quartile was an independent predictor of 1-year mortality in patients with ADHF. Conclusions Poor nutritional status as assessed by NRI and quartile grading of NRI was associated with 1-year mortality in Korean patients with ADHF. The assessment of nutritional status by NRI may provide additional prognostic information and thus would be useful in the risk stratification of the patients with ADHF.

引用

页数：14

共 31 条

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