An induction heating device using planar coil with high amplitude alternating magnetic fields for magnetic hyperthermia

被引：9

作者：

Wu, Zuhe ^{[1
]}

Zhuo, Zihang ^{[1
]}

Cai, Dongyang ^{[1
]}

Wu, Jian'an ^{[1
]}

Wang, Jie ^{[1
]}

Tang, Jintian ^{[1
]}

机构：

[1] Tsinghua Univ, Key Lab Particle Technol & Radiat Imaging, Minist Educ, Dept Engn Phys, Beijing 100084, Peoples R China

来源：

TECHNOLOGY AND HEALTH CARE | 2015年 / 23卷

关键词：

Magnetic hyperthermia; magnetic nanoparticles; planar coil; power abortion; induction heating; NANOPARTICLES;

D O I：

10.3233/THC-150955

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

BACKGROUND: Induction heating devices using the induction coil and magnetic nanoparticles (MNPs) are the way that the magnetic hyperthermia is heading. OBJECTIVE: To facilitate the induction heating of in vivo magnetic nanoparticles in hyperthermia experiments on large animals. METHODS: An induction heating device using a planar coil was designed with a magnetic field frequency of 328 kHz. The coil's magnetic field distribution and the device's induction heating performance on different concentrations of magnetic nanoparticles were measured. RESULTS: The alternating magnetic field produced in the axis position 165 mm away from the coil center is 40 Gs in amplitude; magnetic nanoparticles with a concentration higher than 80 mg. mL-1 can be heated up rapidly. CONCLUSION: Our results demonstrate that the device can be applied not only to in vitro and in small animal experiments of magnetic hyperthermia using MNPs, but also in large animal experiments.

引用

页码：S203 / S209

页数：7

共 29 条

[1] A new method of thermo-chemotherapy using a stent for patients with esophageal cancer [J].