Egg consumption, cardiovascular diseases and type 2 diabetes

被引:62
作者
Geiker, N. R. W. [1 ]
Larsen, M. Lytken [2 ]
Dyerberg, J. [3 ]
Stender, S. [4 ]
Astrup, A. [5 ]
机构
[1] Copenhagen Univ Hosp Herlev Gentofte, Clin Nutr Res Unit, Kildegardsvej 28, DK-2900 Hellerup, Denmark
[2] Aalborg Univ Hosp, Dept Cardiol, Aalborg, Denmark
[3] Univ Copenhagen, Dept Nutr Exercise & Sports Sci, Frederiksberg, Denmark
[4] Copenhagen Univ Hosp Herlev Gentofte, Dept Clin Biochem, Hellerup, Denmark
[5] Univ Copenhagen, Dept Nutr Exercise & Sports Sci, Frederiksberg, Denmark
关键词
CORONARY-HEART-DISEASE; TRIMETHYLAMINE-N-OXIDE; TRANS-FATTY-ACIDS; DIETARY-CHOLESTEROL; SERUM-CHOLESTEROL; DENSITY-LIPOPROTEIN; BUTTERMILK DRINK; STROKE MORTALITY; HDL CHOLESTEROL; ALL-CAUSE;
D O I
10.1038/ejcn.2017.153
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Eggs are rich in nutrients and a source of essential fatty-and amino acids, and the food item with highest cholesterol content. Since the 1970s dietary recommendations have advised limiting egg intake to 2-4 a week for the healthy population, and in those diagnosed with cardiovascular disease (CVD) and type 2 diabetes (T2D) an even more restricted consumption. The aim of the present paper was to assess the recommendation to lower the dietary intake of cholesterol and especially the intake of egg to reduce the risk of CVD and T2D. We performed three web-based literature searches on human studies (observational and interventional) published within the past 10 years during spring 2015. High-quality intervention studies have found nonsignificant effects of increasing the consumption of eggs on risk markers for CVD and T2D in healthy subjects and subjects with T2D. The risk associations found in the observational studies are more likely to be attributed to a dietary pattern often accompanying high egg intake and/or the cluster of other risk factors in people with high egg consumption. Dietary patterns, physical activity and genetics affect the predisposition of CVD and T2D more than a single food item as eggs. In conclusion, up to seven eggs per week can safely be consumed, but in patients with established CVD or T2D only with special emphasis on a healthy lifestyle.
引用
收藏
页码:44 / 56
页数:13
相关论文
共 89 条
[1]   Meta-analysis of Egg Consumption and Risk of Coronary Heart Disease and Stroke [J].
Alexander, Dominik D. ;
Miller, Paula E. ;
Vargas, Ashley J. ;
Weed, Douglas L. ;
Cohen, Sarah S. .
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 2016, 35 (08) :704-716
[2]  
[Anonymous], 2014, QUAL ASS CONTR INT S
[3]  
[Anonymous], 2012, DET ER AEGG LET
[4]  
[Anonymous], 2005, Dietary Guidelines for Americans 2005
[5]   The role of higher protein diets in weight control and obesity-related comorbidities [J].
Astrup, A. ;
Raben, A. ;
Geiker, N. .
INTERNATIONAL JOURNAL OF OBESITY, 2015, 39 (05) :721-726
[6]  
Atkins D, 2004, BMJ-BRIT MED J, V328, P1490
[7]   The influence of consuming an egg or an egg-yolk buttermilk drink for 12 wk on serum lipids, inflammation, and liver function markers in human volunteers [J].
Baumgartner, Sabine ;
Kelly, Elton R. ;
van der Made, Sanne ;
Berendschot, Tos T. J. M. ;
Husche, Constanze ;
Luetjohann, Dieter ;
Plat, Jogchum .
NUTRITION, 2013, 29 (10) :1237-1244
[8]   Consumption of industrial and ruminant trans fatty acids and risk of coronary heart disease: a systematic review and meta-analysis of cohort studies [J].
Bendsen, N. T. ;
Christensen, R. ;
Bartels, E. M. ;
Astrup, A. .
EUROPEAN JOURNAL OF CLINICAL NUTRITION, 2011, 65 (07) :773-783
[9]   Dietary cholesterol and cardiovascular disease: a systematic review and meta-analysis [J].
Berger, Samantha ;
Raman, Gowri ;
Vishwanathan, Rohini ;
Jacques, Paul F. ;
Johnson, Elizabeth J. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2015, 102 (02) :276-294
[10]   Dietary Protein Sources and the Risk of Stroke in Men and Women [J].
Bernstein, Adam M. ;
Pan, An ;
Rexrode, Kathryn M. ;
Stampfer, Meir ;
Hu, Frank B. ;
Mozaffarian, Dariush ;
Willett, Walter C. .
STROKE, 2012, 43 (03) :637-+