The Potential Vaccine Component for COVID-19: A Comprehensive Review of Global Vaccine Development Efforts

被引：11

作者：

Khan, Israr ^{[1
]}

Ahmed, Zahoor ^{[2
]}

Sarwar, Ayesha ^{[2
]}

Jamil, Abdur ^{[3
]}

Anwer, Faiz ^{[4
]}

机构：

[1] Bolan Med Coll, Internal Med, Quetta, Pakistan

[2] King Edward Med Univ, Mayo Hosp, Internal Med, Lahore, Pakistan

[3] Cent Michigan Univ, Internal Med, Saginaw, MI USA

[4] Cleveland Clin, Hematol & Oncol, Cleveland, OH 44106 USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2020年 / 12卷 / 06期

关键词：

coronavirus; covid-19; sars-cov-2; vaccine; SARS; 2019-NCOV; SPIKE;

D O I：

10.7759/cureus.8871

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The whole world is concerned about the pandemic of coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), due to fatality of this condition. This has become a public health emergency of international concern. No specific vaccine and medicine have proven effective in large-sized trials at this time. With the rapidly increasing number of positive cases and deaths, there is a dire need for effective treatments and an effective vaccine for prevention. An urgent unmet need led to the planning and opening of multiple drug development trials for treatment and vaccine development. In this article, we have summarized data on cell receptor interactions and data on prospects of new vaccines targeting the deoxyribonucleic acid (DNA), messenger ribonucleic acid (mRNA), and viral minigenes. We have tabulated the available data on various clinical trials testing various aspects of COVID-19 vaccines.

引用

页数：8

共 27 条

[1] Global patterns in coronavirus diversity [J].