What is the role of bronchial thermoplasty in the management of severe asthma?

被引：8
作者：
O'Reilly, Aoife [1 ]
Lane, Stephen [1 ]
机构：
[1] Tallaght Hosp, Dublin D24 NR0A 24, Ireland
来源：
THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE | 2018年 / 12卷
关键词：
asthma; bronchial hyperresponsiveness; airway smooth muscle; bronchial thermoplasty; bronchoscopic procedure; AIRWAY SMOOTH-MUSCLE; SEVERE PERSISTENT ASTHMA; SAFETY; EFFICACY;
D O I：
10.1177/1753466618792410
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Asthma is a common chronic inflammatory condition of the airways. Conventional therapy comprises inhaled corticosteroid and bronchodilators as well as trigger avoidance and management of comorbid conditions. A small group remain symptomatic despite these strategies and novel therapies have been developed. Bronchial thermoplasty is a nonpharmacological therapy which targets airway smooth muscle to improve asthma control. Clinical trials to date have shown the efficacy and safety of bronchial thermoplasty with a persistent effect on extended follow up. Questions remain regarding the exact mechanism of action of bronchial thermoplasty, the cost effectiveness of the procedure and the ideal criteria for patient selection.
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页数：7
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