This article describes the theoretical perspectives and the empirical research relating personal dispositions, resources, appraisals, and coping processes to stress-related growth and thriving within a transactional stress and coping framework. Following a description of this framework, the personal characteristics relevant to thriving and growth are reviewed. It is noted that personal characteristics may exert effects directly on positive outcomes such as thriving and growth, and that the effects of these personal characteristics may also be mediated by various appraisal and coping processes. Theoretical and empirical work on appraisal and coping processes as predictors of growth and thriving are then reviewed. Work on comprehensive models of stress-related growth and thriving that include personal resources and coping processes is discussed; such models consider appraisal and coping processes as potential mechanisms through which personal characteristics may operate indirectly to affect stress-related growth and thriving. Finally, some implications of these relationships for individuals and for communities are suggested.