Sigmoidine L, a new antibacterial flavonoid from Erythrina sigmoidea (Fabaceae)

被引：0
作者：
Kouam, Jacques
Etoa, Francois-Xavier
Mabeku, Laure BrigitteKouitcheu
Fomum, Zacharias Tanee
机构：
[1] Univ Yaounde 1, Fac Sci, Dept Organ Chem, Yaounde, Cameroon
[2] Univ Yaounde 1, Fac Sci, Microbiol Lab, Dept Biochem, Yaounde, Cameroon
来源：
NATURAL PRODUCT COMMUNICATIONS | 2007年 / 2卷 / 11期
关键词：
Erythrina sigmoidea; Fabaceae; stem bark; flavonoid;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Chemical analyses of the stem bark of Erythrina sigmoidea (Fabaceae) yielded a new flavonoid, designated sigmoidin L (1), the known erythrinasinate, E-p-coumaric acid docosylester, and 3'-prenylnaringinin, reported here for the first time for the stem bark of E.sigmoidea. The structure of I was established by chemical and spectroscopic means as 5,7, 3',4'-tetrahydroxy-5'-[3"-methyl-4"-oxobut-(1"Z) enyl]flavanone. Sigmoidin L exhibited significant antibacterial potency in vitro against Staphylococus aureus and Proteus vulgaris.
引用
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页码：1105 / 1108
页数：4
相关论文
共 11 条
  • [1] ATTAURRAHMAN, 1986, NUCL MAGNETIC RESONA, P81
  • [2] FOMUM ZT, 1986, PHYTOCHEMISTRY, V25, P757, DOI 10.1016/0031-9422(86)88044-X
  • [3] HANS A, 1986, Z FUER NATURFORSCHUN, V42, P164
  • [4] A comparative study of the flavonoids and some biological activities of two Chenopodium species
    Ibrahim, L. F.
    Kawashty, S. A.
    Baiuomy, Ayman R.
    Shabana, M. M.
    El-Eraky, W. I.
    El-Negoumy, S. I.
    [J]. CHEMISTRY OF NATURAL COMPOUNDS, 2007, 43 (01) : 24 - 28
  • [5] KAMDEM WAF, 2006, PHYTOCHEMISTRY, V67, P459
  • [6] Kouitcheu MLB, 2007, AFR J TRADIT COMPLEM, V4, P87
  • [7] Flavonoids and biological activities of Jussiaea repens
    Marzouk, M. S.
    Soliman, F. M.
    Shehata, I. A.
    Rabee, M.
    Fawzy, G. A.
    [J]. NATURAL PRODUCT RESEARCH, 2007, 21 (05) : 436 - 443
  • [8] ERYTHRINA STUDIES .30. SIGMOIDIN-J AND SIGMOIDIN-K, 2 NEW PRENYLATED ISOFLAVONOIDS FROM ERYTHRINA-SIGMOIDEA
    NKENGFACK, AE
    VOUFFO, TW
    VARDAMIDES, JC
    FOMUM, ZT
    BERGENDORFF, O
    STERNER, O
    [J]. JOURNAL OF NATURAL PRODUCTS, 1994, 57 (08): : 1172 - 1177
  • [9] ERYTHRINA STUDIES .21. FURTHER FLAVONOIDS FROM ERYTHRINA SPECIES
    NKENGFACK, AE
    KOUAM, J
    VOUFFO, WT
    FOMUM, ZT
    DAGNE, E
    STERNER, O
    BROWNE, LM
    JI, GJ
    [J]. PHYTOCHEMISTRY, 1993, 32 (05) : 1305 - 1311
  • [10] ERYTHRINA STUDIES .13. 2 NEW FLAVONOIDS FROM ERYTHRINA-ERIOTRIOCHA
    NKENGFACK, AE
    SANSON, DR
    TEMPESTA, MS
    FOMUM, ZT
    [J]. JOURNAL OF NATURAL PRODUCTS, 1989, 52 (02): : 320 - 324
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