Activity survey and historical perspective of autologous stem cell transplantation in Europe

被引：10

作者：

Gratwohl, Alois ^{[1
]}

机构：

[1] Univ Basel Hosp, European Grp Blood & Marrow Transplatat Act Surve, CH-4031 Basel, Switzerland

来源：

SEMINARS IN HEMATOLOGY | 2007年 / 44卷 / 04期

关键词：

D O I：

10.1053/j.seminhematol.2007.09.001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Autologous hematopoietic stem cell transplantation (HSCT) has a long tradition in Europe. Initially developed as a tool to restore rapid remission or chronic phase in patients with advanced leukemia without a sibling donor, it evolved over the last three decades to be used as a standard tool in patients with malignancies that are responsive to high-dose chemoradiotherapy. Autologous HSCTs are the standard of care for defined patients with lymphoid malignancies and for certain solid tumors of childhood. They continue to be evaluated in acute myeloid leukemia and are being investigated in phase II and III studies for defined severe autoimmune disorders. More than 15,000 such procedures, mainly peripheral blood stem cell transplants, are performed annually in Europe, which corresponds to double the number of allogeneic HSCTs. These numbers emphasize the important role of this type of therapy at its current stage. © 2007 Elsevier Inc. All rights reserved.

引用

页码：220 / 226

页数：7

共 39 条

[1]

APPELBAUM FR, 1986, CLIN HAEMATOL, V15, P1

[2] Single versus double autologous stem-cell transplantation for multiple myeloma [J].

Attal, M ;

Harousseau, JL ;

Facon, T ;

Guilhot, F ;

Doyen, C ;

Fuzibet, JG ;

Monconduit, M ;

Hulin, C ;

Caillot, D ;

Bouabdallah, R ;

Voillat, L ;

Sotto, JJ ;

Grosbois, B ;

Bataille, R .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (26) :2495-2502

[3]

BACH FH, 1968, LANCET, V2, P1364

[4]

BOWLES CA, 1980, J NATL CANCER I, V65, P615

[5] Autologous bone marrow transplantation as consolidation therapy in the treatment of adult patients under 60 years with acute myeloid leukaemia in first complete remission:: a prospective randomized Dutch-Belgian Haemato-Oncology Co-operative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK) trial [J].

Breems, DA ;

Boogaerts, MA ;

Dekker, AW ;

Van Putten, WLJ ;

Sonneveld, P ;

Huijgens, PC ;

Van der Lelie, J ;

Vellenga, E ;

Gratwohl, A ;

Verhoef, GEG ;

Verdonck, LF ;

Löwenberg, B .

BRITISH JOURNAL OF HAEMATOLOGY, 2005, 128 (01) :59-65

[6]

BUCKNER CD, 1974, EXP HEMATOL, V2, P138

[7] Medical progress: Hematopoietic stem-cell transplantation [J].

Copelan, EA .

NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (17) :1813-1826

[8] Cell therapy for autoimmune diseases [J].

Dazzi, Francesco ;

van Laar, Jacob M. ;

Cope, Andrew ;

Tyndall, Alan .

ARTHRITIS RESEARCH & THERAPY, 2007, 9 (02)

[9]

de Witte T, 2006, HAEMATOLOGICA, V91, P750

[10]

Farquhar C, 2005, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD003142.pub2, 10.1002/14651858.CD003139.pub2, 10.1002/14651858.CD004143.pub2, 10.1002/14651858.CD001122.pub2]

← 1 2 3 4 →