AKT-mediated phosphorylation is responsible for TWIST1-mediated tumor growth and metastasis

被引:0
|
作者
Ozes, Osman N. [1 ]
Pehivanoglu, Suray [1 ]
Ertosun, Gokhan [1 ]
Gorgisen, Gokhan [1 ]
Erin, Nuray [1 ]
Unal, Duygu [1 ]
Tanriover, Gamze [1 ]
机构
[1] Akdeniz Univ, TR-07058 Antalya, Turkey
关键词
D O I
10.1158/1538-7445.AM2014-1130
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1130
引用
收藏
页数:1
相关论文
共 50 条
  • [21] SGO1 induces proliferation and metastasis of prostate cancer through AKT-mediated signaling pathway
    Chen, Qi
    Wan, Xiang
    Chen, Yanbo
    Liu, Chong
    Gu, Meng
    Wang, Zhong
    AMERICAN JOURNAL OF CANCER RESEARCH, 2019, 9 (12): : 2693 - +
  • [22] Nuclear import of hTERT requires a bipartite nuclear localization signal and Akt-mediated phosphorylation
    Chung, Jeeyun
    Khadka, Prabhat
    Chung, In Kwon
    JOURNAL OF CELL SCIENCE, 2012, 125 (11) : 2684 - 2697
  • [23] Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation
    Jeong, Sun Ah
    Kim, Kuglae
    Lee, Ji Hoon
    Cha, Jeong Seok
    Khadka, Prabhat
    Cho, Hyun-Soo
    Chung, Kwon
    JOURNAL OF CELL SCIENCE, 2015, 128 (12) : 2287 - 2301
  • [24] AKT-mediated regulation of chromatin ubiquitylation and tumorigenesis through Mel18 phosphorylation
    Jia Mai
    Xiao-Dan Peng
    Jun Tang
    Tian Du
    Yu-Hong Chen
    Zi-Feng Wang
    Hai-Liang Zhang
    Jun-Hao Huang
    Zhuo-Yan Zhong
    Dong Yang
    Zhi-Ling Li
    Yun Huang
    Gong-Kan Feng
    Xiao-Feng Zhu
    Rong Deng
    Oncogene, 2021, 40 : 2422 - 2436
  • [25] Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition
    Gabriel G Malouf
    Joseph H Taube
    Yue Lu
    Tapasree Roysarkar
    Shoghag Panjarian
    Marcos RH Estecio
    Jaroslav Jelinek
    Jumpei Yamazaki
    Noel J-M Raynal
    Hai Long
    Tomomitsu Tahara
    Agata Tinnirello
    Priyanka Ramachandran
    Xiu-Ying Zhang
    Shoudan Liang
    Sendurai A Mani
    Jean-Pierre J Issa
    Genome Biology, 14
  • [26] TWIST1-MEDIATED ENDOTHELIAL PLASTICITY DRIVES GLIOBLASTOMA RESISTANCE TO CAR T IMMUNOTHERAPY
    Yang, Fan
    Akhtar, Md Naushad
    Gong, Yanqing
    Fan, Yi
    NEURO-ONCOLOGY, 2024, 26
  • [27] Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins
    Bouchard, C
    Marquardt, J
    Brás, A
    Medema, RH
    Eilers, M
    EMBO JOURNAL, 2004, 23 (14): : 2830 - 2840
  • [28] AKT-mediated regulation of chromatin ubiquitylation and tumorigenesis through Mel18 phosphorylation
    Mai, Jia
    Peng, Xiao-Dan
    Tang, Jun
    Du, Tian
    Chen, Yu-Hong
    Wang, Zi-Feng
    Zhang, Hai-Liang
    Huang, Jun-Hao
    Zhong, Zhuo-Yan
    Yang, Dong
    Li, Zhi-Ling
    Huang, Yun
    Feng, Gong-Kan
    Zhu, Xiao-Feng
    Deng, Rong
    ONCOGENE, 2021, 40 (13) : 2422 - 2436
  • [29] Direct stimulation of NADP+ synthesis through Akt-mediated phosphorylation of NAD kinase
    Hoxhaj, Gerta
    Ben-Sahra, Issam
    Lockwood, Sophie E.
    Timson, Rebecca C.
    Byles, Vanessa
    Henning, Graham T.
    Gao, Peng
    Selfors, Laura M.
    Asara, John M.
    Manning, Brendan D.
    SCIENCE, 2019, 363 (6431) : 1088 - +
  • [30] ACOT4 accumulation via AKT-mediated phosphorylation promotes pancreatic tumourigenesis
    Ni, Chenming
    Zheng, Kailian
    Gao, Yunshu
    Chen, Ying
    Shi, Keqing
    Ni, Canrong
    Jin, Gang
    Yu, Guanzhen
    CANCER LETTERS, 2021, 498 : 19 - 30