Why NAD+ Declines during Aging: It's Destroyed

被引:102
作者
Schultz, Michael B. [1 ]
Sinclair, David A. [1 ,2 ]
机构
[1] Harvard Univ, Sch Med, Dept Genet, Paul F Glenn Ctr Biol Mech Aging, Boston, MA 02115 USA
[2] Univ New S Wales, Dept Pharmacol, Sydney, NSW 2052, Australia
关键词
METABOLISM;
D O I
10.1016/j.cmet.2016.05.022
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
NAD(+) is required not only for life but for a long life. In this issue, Camacho-Pereira et al. (2016) implicate CD38 in the decline of NAD(+) during aging, with implications for combating age-related diseases.
引用
收藏
页码:965 / 966
页数:2
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