Palladium-Catalyzed Asymmetric 1,6-Addition of Diarylphosphines to Allylidenemalonates for Chiral Phosphine Synthesis

被引：11
作者：
Wei, Xu [1 ]
Lu, Junzhu [2 ]
Duan, Wei-Liang [3 ]
机构：
[1] Shanghai Inst Technol, Sch Chem & Environm Engn, Shanghai 201418, Peoples R China
[2] East China Univ Sci & Technol, Sch Pharm, 130 Meilong Rd, Shanghai 200237, Peoples R China
[3] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China
来源：
SYNTHESIS-STUTTGART | 2016年 / 48卷 / 23期
基金：
美国国家科学基金会;
关键词：
asymmetric 1,6-addition; pincer palladium catalyst; chiral phosphines; allylidenemalonates; BAYLIS-HILLMAN CARBONATES; PCN PINCER PALLADIUM(II); P-STEREOGENIC PHOSPHINES; ENANTIOSELECTIVE SYNTHESIS; 1,6-CONJUGATE ADDITION; SECONDARY PHOSPHINES; ACTIVATED OLEFINS; ARYLBORONIC ACIDS; MICHAEL REACTION; SULFONIC ESTERS;
D O I：
10.1055/s-0035-1562456
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A pincer-palladium-catalyzed asymmetric 1,6-addition of diarylphosphines to allylidenemalonates has been developed for the synthesis of chiral allylic phosphines with up to 89% ee under mild conditions.
引用
收藏
页码：4155 / 4160
页数：6
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