CONVENIENT METHOD FOR REDUCTION OF C-N DOUBLE BONDS IN OXIMES, IMINES, AND HYDRAZONES USING SODIUM BOROHYDRIDE-RANEY Ni SYSTEM

被引：11

作者：

Yang, Yihua ^{[1
]}

Liu, Shouxin ^{[1
]}

Li, Junzhang ^{[1
]}

Tian, Xia ^{[2
]}

Zhen, Xiaoli ^{[2
]}

Han, Jianrong ^{[2
]}

机构：

[1] Hebei Univ Sci & Technol, Coll Chem & Pharmaceut Engn, Shijiazhuang 050018, Peoples R China

[2] Hebei Univ Sci & Technol, Coll Sci, Shijiazhuang 050018, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2012年 / 42卷 / 17期

基金：

中国国家自然科学基金;

关键词：

C-N double bond; Raney Ni; reduction; sodium borohydride; O-ALKYL ETHERS; ASYMMETRIC REDUCTION; EFFICIENT SYNTHESIS; ESTERS; REACTIVITY; AMINATION; CHLORIDE; LIGANDS; NICKEL;

D O I：

10.1080/00397911.2011.562063

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A practical method has been developed for reduction of C-N double bond in oximes, imines, and hydrazones with sodium borohydride catalyzed by Raney Ni. The reactions were carried out in basic aqueous solution, and the desired products were obtained in moderate yields after a simple procedure. This method can be applied to synthesize simpler aliphatic or aromatic amines and its analogs.

引用

页码：2540 / 2554

页数：15

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