Integrating host genomics with surveillance for invasive bacterial diseases

被引：5

作者：

Crawford, Dana C. ^{[2
]}

Zimmer, Shanta M. ^{[3
]}

Morin, Craig A. ^{[4
]}

Messonnier, Nancy E. ^{[5
]}

Lynfield, Ruth ^{[4
]}

Yi, Qian

Shephard, Cynthia

Wong, Michelle

Rieder, Mark J.

Livingston, Robert J.

Nickerson, Deborah A.

Whitney, Cynthia G. ^{[5
]}

Lingappa, Jairam ^{[1
]}

机构：

[1] Univ Washington, Dept Med, Seattle, WA 98195 USA

[2] Vanderbilt Univ, Ctr Human Genet Res, Nashville, TN USA

[3] Emory Univ, Atlanta, GA 30322 USA

[4] Minnesota Dept Hlth, St Paul, MN USA

[5] Ctr Dis Control & Prevent, Atlanta, GA USA

来源：

EMERGING INFECTIOUS DISEASES | 2008年 / 14卷 / 07期

关键词：

D O I：

10.3201/eid1407.071287

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We tested the feasibility of linking Active Bacterial Core surveillance, a prospective, population-based surveillance system for invasive bacterial disease, to a newborn dried blood spot (nDBS) repository. Using nDBS specimens, we resequenced CD46, putative host gene receptor for Neisseria meningitidis, and identified variants associated with susceptibility to this disease.

引用

页码：1138 / 1140

页数：3

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