Unmasking dermatofibrosarcoma protuberans: Case report of an atypical presentation complicated by post-surgical excision

被引:3
作者
Zhou , YaQun [1 ,2 ]
Chin, Justin [1 ,3 ]
Strutin, Millard D. [2 ]
Lomiguen, Christine M. [4 ]
机构
[1] Touro Coll Osteopath Med, Dept Primary Care, New York, NY 10027 USA
[2] St Clares Denville Hosp, Dept Surg, Denville, NJ USA
[3] Lifelong Med Care, Dept Family Med, Richmond, CA USA
[4] Lake Erie Coll Osteopath Med, Dept Pathol, Erie, PA USA
来源
INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS | 2020年 / 69卷
关键词
Dermatofibrosarcoma protuberans; DFSP; Soft tissue tumor; Lipoma; CD34; Case report; WIDE LOCAL EXCISION; COL1A1-PDGFB; DIAGNOSIS; FUSION;
D O I
10.1016/j.ijscr.2020.03.020
中图分类号
R61 [外科手术学];
学科分类号
摘要
INTRODUCTION: Dermatofibrosarcoma Protuberans (DFSP) is a rare type of malignant tumor of the cutaneous soft tissue that typically involves the dermis and surrounding structures. The typical clinical presentation involves an asymptomatic, slowly enlarging, indurated plaque, usually found on the trunk. PRESENTATION OF CASE: Here we present an atypical presentation of DFSP in a patient with a recurrent mass that was initially diagnosed as a lipoma, with supporting literature and clinical considerations for post-surgical management DISCUSSION: In its earlier stages, DFSP can mimic other benign or malignant dermatological pathologies, which can complicate diagnosis purely via history and physical exam. Atypical features such as prior surgical management, morphology, and location can complicate the clinical diagnosis of DFSP. Immunohistochemistry is often required for definitive diagnosis as DFSP is CD34+ and is histologically described as spindle-cells in whorled or storiform pattern, with uniform, small elongated cells. CONCLUSION: DFSP is a rare tumor of the skin and subcutaneous tissue. Though it commonly presents with induration, skin discoloration, and telangiectasias, it is important to keep DFSP as a differential in new masses found on previous surgical sites, especially if the previous mass had a possibility of recurrence. (C) 2020 The Author( s). Published by Elsevier Ltd on behalf of BS Publishing Group Ltd.
引用
收藏
页码:101 / 104
页数:4
相关论文
共 20 条
  • [1] Dermatofibrosarcoma Protuberans
    Acosta, Alvaro E.
    Santa Velez, Catalina
    [J]. CURRENT TREATMENT OPTIONS IN ONCOLOGY, 2017, 18 (09)
  • [2] The SCARE 2018 statement: Updating consensus Surgical CAse REport (SCARE) guidelines
    Agha, Riaz A.
    Borrelli, Mimi R.
    Farwana, Reem
    Koshy, Kiron
    Fowler, Alexander J.
    Orgill, Dennis P.
    Zhu, Hongyi
    Alsawadi, Abdulrahman
    Noureldin, Ashraf
    Rao, Ashwini
    Enam, Ather
    Thoma, Achilleas
    Bashashati, Mohammad
    Vasudevan, Baskaran
    Beamish, Andrew
    Challacombe, Ben
    De Wilde, Rudy Leon
    Machado-Aranda, David
    Laskin, Daniel
    Muzumdar, Dattatraya
    D'cruz, Anil
    Manning, Todd
    Healy, Donagh
    Pagano, Duilio
    Goel, Prabudh
    Ranganathan, Priya
    Pai, Prathamesh S.
    Raja, Shahzad
    Athe, M. Hammad
    Kadioazlu, Huseyin
    Nixon, Iain
    Mukherjee, Indraneil
    Gomez Riva, Juan
    Raveendran, Kandiah
    Derbyshire, Laura
    Valmasoni, Michele
    Chalkoo, Mushtaq
    Raison, Nicholas
    Muensterer, Oliver
    Bradley, Patrick
    Roberto, Coppola
    Afifi, Raafat
    Rosin, David
    Klappenbach, Roberto
    Wynn, Rolf
    Giordano, Salvatore
    Basu, Somprakas
    Surani, Salim
    Suman, Paritosh
    Thorat, Mangesh
    [J]. INTERNATIONAL JOURNAL OF SURGERY, 2018, 60 : 132 - 136
  • [3] [Anonymous], 2019, ANN SURG
  • [4] Bowne WB, 2000, CANCER, V88, P2711
  • [5] Dermatofibrosarcoma Protuberans Treated With Wide Local Excision and Followed at a Cancer Hospital: Prognostic Significance of Clinicopathologic Variables
    Erdem, Ozlem
    Wyatt, Angela J.
    Lin, E.
    Wang, Xuemei
    Prieto, Victor G.
    [J]. AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2012, 34 (01) : 24 - 34
  • [6] Dermatofibrosarcoma Protuberans of the Neck: A Brief Review of the Literature
    Felek, Sevim Aslan
    Ibas, Mustafa
    Dursun, Songul
    Heper, Aylin Okcu
    [J]. INDIAN JOURNAL OF OTOLARYNGOLOGY AND HEAD & NECK SURGERY, 2019, 71 (Suppl 1) : 369 - 372
  • [7] CD34 and factor-XIIIa immunoreactivity in dermatofibrosarcoma protuberans and dermatofibroma
    Goldblum, JR
    Tuthill, RJ
    [J]. AMERICAN JOURNAL OF DERMATOPATHOLOGY, 1997, 19 (02) : 147 - 153
  • [8] Immunohistochemical characterization of dermatofibrosarcoma protuberans with practical applications for diagnosis and treatment
    Haycox, CL
    Odland, PB
    Olbricht, SM
    Piepkorn, M
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1997, 37 (03) : 438 - 444
  • [9] Dermatofibrosarcoma protuberans: Two rare variants
    Jain, Sarina
    Dashore, Shuken
    Singhania, Bharat
    Khopkar, Uday S.
    Darkase, Bhushan
    [J]. INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY, 2019, 85 (02) : 204 - 208
  • [10] Dermatofibrosarcoma protuberans: Reappraisal of wide local excision and impact of inadequate initial treatment
    Khatri, VP
    Galante, JM
    Bold, RJ
    Schneider, PD
    Ramsamooj, R
    Goodnight, JE
    [J]. ANNALS OF SURGICAL ONCOLOGY, 2003, 10 (09) : 1118 - 1122