Impact of Diabetes Mellitus on Critical Limb Ischemia With Below the Knee Disease: Japan Below-the-Knee Artery Treatment Subanalysis

被引：10

作者：

Suzuki, Kenji ^{[1
]}

Iida, Osamu ^{[2
]}

Yamauchi, Yasutaka ^{[3
]}

Nakano, Masatsugu ^{[4
]}

Soga, Yoshimitsu ^{[5
]}

Kawasaki, Daizo ^{[6
]}

Tazaki, Junichi ^{[7
]}

Yamaoka, Terutoshi ^{[8
]}

Suematsu, Nobuhiro ^{[9
]}

Shintani, Yoshiaki ^{[10
]}

Miyashita, Yusuke ^{[11
]}

Inoue, Naoto ^{[1
]}

Meguro, Taiichiro ^{[1
]}

机构：

[1] Sendai Kousei Hosp, Cardiovasc Ctr, Aoba Ku, 4-15 Hirosemachi, Sendai, Miyagi 9800873, Japan

[2] Kansai Rosai Hosp, Cardiovasc Div, Amagasaki, Hyogo, Japan

[3] Kikuna Mem Hosp, Cardiovasc Ctr, Kohoku Ku, Yokohama, Kanagawa, Japan

[4] Saiseikai Yokohama City Eastern Hosp, Dept Cardiol, Tsurumi Ku, Yokohama, Kanagawa, Japan

[5] Kokura Mem Hosp, Dept Cardiol, Kita Ku, Kibune Cho, Kitakyushu, Fukuoka, Japan

[6] Hyogo Coll Med, Dept Internal Med, Cardiovasc Div, Mukogawa Cho, Nishinomiya, Hyogo, Japan

[7] Kyoto Univ Hosp, Dept Circulatory Organs, Sakyo Ku, Kawahara Cho, Kyoto, Kyoto, Japan

[8] Matsuyama Red Cross Hosp, Dept Vasc Surg, Bunkyo Cho, Matsuyama, Ehime, Japan

[9] Japanese Red Cross Fukuoka Hosp, Dept Cardiol, Minami Ku, Okusu Cho, Fukuoka, Fukuoka, Japan

[10] Shin Koga Hosp, Dept Cardiol, Tenjin Cho, Kurume, Fukuoka, Japan

[11] Shinshu Univ Hosp, Dept Adv PAD Therapeut, Asahi Ku, Matsumoto, Nagano, Japan

来源：

ANGIOLOGY | 2020年 / 71卷 / 05期

关键词：

endovascular therapy; peripheral arterial disease; diabetes mellitus; critical limb ischemia; SKIN PERFUSION-PRESSURE; BALLOON-ANGIOPLASTY; LEG BASIL; BYPASS; MULTICENTER; CILOSTAZOL; PATENCY;

D O I：

10.1177/0003319713499606

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Background: A strong association exists between diabetes mellitus and critical limb ischemia. Methods and Results: We performed endovascular therapy on 1060 limbs in 884 patients with below knee lesions only. The patients were divided into diabetes (DG) and nondiabetes groups (NDG). Limb salvage was poorer in the DG (79% vs 89%, P = .0061). No significant difference was observed in mortality, amputation-free survival (AFS), and target vessel revascularization (TVR). Multivariate analysis revealed diabetes status, infection, poor activity of daily living (ADL), younger age, and procedure failure as independent predictors of major amputation in DG. In the NDG, procedure failure was the predictor, and younger age and poor ADL showed tendency of major amputation. Conclusions: Mortality, AFS, and TVR showed no significant difference between the 2 groups, but major amputation was more frequent in DG. Not only revascularization but also infection and diabetes control were very important for limb salvage in DG.

引用

页码：444 / 451

页数：8

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