TGF-β-Induced Epigenetic Silencing of SOCS3 Facilitates STAT3 Signaling to Promote Fibroblast Activation and Tissue Fibrosis in Systemic Sclerosis

被引:0
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作者
Dees, Clara [1 ,2 ]
Zhang, Yun [3 ,4 ,5 ,6 ]
Poetter, Sebastian [1 ,2 ]
Bergmann, Christina [3 ,5 ,6 ]
Ramming, Andreas [6 ,7 ]
Distler, Oliver [8 ]
Schett, Georg [7 ]
Distler, Joerg [7 ]
机构
[1] Univ Erlangen Nurnberg, Dept Internal Med 3, Erlangen, Germany
[2] Univ Erlangen Nurnberg, Inst Clin Immunol, Erlangen, Germany
[3] Friedrich Alexander Univ Erlangen Nuremberg, Dept Internal Med 3, Erlangen, Germany
[4] Friedrich Alexander Univ Erlangen Nuremberg, Inst Clin Immunol, Dept Internal Med 3, Erlangen, Germany
[5] Friedrich Alexander Univ Erlangen Nuremberg, Inst Clin Immunol, Erlangen, Germany
[6] Univ Hosp Erlangen, Erlangen, Germany
[7] Friedrich Alexander Univ Erlangen Nurnberg FAU, Univ Klinikum Erlangen, Dept Internal Med Rheumatol & Immunol 3, Erlangen, Germany
[8] Univ Hosp Zurich, Dept Rheumatol, Zurich, Switzerland
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R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
826
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页数:3
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