Synovial cytokine mRNA expression during arthritis triggered by CpG motifs of bacterial DNA

被引：16

作者：

Deng, GM ^{[1
]}

Tarkowski, A ^{[1
]}

机构：

[1] Gothenburg Univ, Dept Rheumatol, S-41346 Gothenburg, Sweden

来源：

ARTHRITIS RESEARCH | 2001年 / 3卷 / 01期

关键词：

arthritis; CpG dinucleotides; cytokine; IL-12; knockout;

D O I：

10.1186/ar139

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Our results show that cytokines derived from macrophages play an important role in pathogenesis of arthritis triggered by CpG oligodinucleotide (CpG ODN). IL-12 is in this respect an important immunomodulator during the development of joint inflammation.

引用

页码：48 / 53

页数：6

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