Asymmetric Michael addition of aldehydes to maleimides in primary amine-based aqueous ionic liquid-supported recyclable catalytic system

被引：11

作者：

Kochetkov, Sergei V. ^{[1
]}

Kucherenko, Alexander S. ^{[1
]}

Zlotin, Sergei G. ^{[1
]}

机构：

[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, Moscow 119991, Russia

来源：

MENDELEEV COMMUNICATIONS | 2017年 / 27卷 / 05期

基金：

俄罗斯科学基金会;

关键词：

ENANTIOSELECTIVE CONJUGATE ADDITION; ALPHA; ALPHA-DISUBSTITUTED ALDEHYDES; GAMMA-LACTAMS; 1,3-DICARBONYL COMPOUNDS; ORGANOCATALYST; INHIBITORS; GUANIDINE; NUCLEOPHILES; ALKALOIDS; SOLVENTS;

D O I：

10.1016/j.mencom.2017.09.014

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A primary amine-based aqueous ionic liquid-supported recyclable catalytic system for asymmetric Michael addition of aldehydes to maleimides has been developed. The best enantioselectivity (up to 84% ee) was attained at the [bmim]BF4/water 2 : 1 (v/v) ratio.

引用

页码：473 / 475

页数：3

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