Clinical Usefulness of Therapeutic Neuromodulation for Major Depression A Systematic Meta-Review of Recent Meta-Analyses

被引：36
作者：
McGirr, Alexander [1 ]
Berlim, Marcelo T. [2 ]
机构：
[1] Univ Calgary, Hotchkiss Brain Inst, Mathison Ctr Mental Hlth Res & Educ, Dept Psychiat, TRW 4D68,3280 Hosp Dr Northwest, Calgary, AB T2N 4Z6, Canada
[2] McGill Univ, Douglas Mental Hlth Univ Inst, Neuromodulat Res Clin, Depress Disorders Program, 6875 LaSalle Blvd, Montreal, PQ H4H 1R3, Canada
来源：
PSYCHIATRIC CLINICS OF NORTH AMERICA | 2018年 / 41卷 / 03期
关键词：
Major depression; Treatment-resistant depression; Neuromodulation; Brain stimulation; Repetitive transcranial magnetic stimulation; Transcranial direct current stimulation; Vagus nerve stimulation; Deep brain stimulation; TRANSCRANIAL MAGNETIC STIMULATION; TREATMENT-RESISTANT DEPRESSION; DEEP BRAIN-STIMULATION; THETA-BURST STIMULATION; VAGUS NERVE-STIMULATION; DOUBLE-BLIND; ELECTROCONVULSIVE-THERAPY; PREFRONTAL CORTEX; EXPLORATORY METAANALYSIS; EFFICACY;
D O I：
10.1016/j.psc.2018.04.009
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
The authors conducted a metareview of meta-analyses published in the past decade on therapeutic neuromodulation (ie, repetitive transcranial magnetic stimulation, transcranial direct current stimulation, vagus nerve stimulation, and deep brain stimulation) for major depression. Active repetitive transcranial magnetic stimulation and transcranial direct current stimulation have been generally associated with small to moderate effect sizes vis-a-vis their efficacy and with similar acceptability compared with sham. Vagus nerve stimulation and deep brain stimulation (although more challenging to investigate) have demonstrated preliminary effectiveness, particularly during longer-term follow-up.
引用
收藏
页码：485 / +
页数：20
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