Serological evidence of Histoplasma capsulatum infection among dogs with leishmaniasis in Brazil

被引:8
作者
Cordeiro, R. A. [1 ]
Coelho, C. G. V. [1 ,3 ]
Brilhante, R. S. N. [1 ]
Sidrim, J. J. C. [1 ]
Castelo-Branco, D. S. C. M. [1 ]
Moura, F. B. P. [4 ]
Rocha, F. A. C. [5 ]
Rocha, M. F. G. [1 ,2 ]
机构
[1] Univ Fed Ceara, Specialized Med Mycol Ctr, Sch Med, Dept Pathol & Legal Med, BR-60430275 Fortaleza, Ceara, Brazil
[2] Univ Estadual Ceara, Sch Vet Med, Postgrad Program Vet Sci, Fortaleza, Ceara, Brazil
[3] Univ Fed Ceara, Sch Med, Sobral, CE, Brazil
[4] State Hlth Dept, Fortaleza, Ceara, Brazil
[5] Univ Fed Ceara, Fac Med, Dept Internal Med, BR-60430275 Fortaleza, Ceara, Brazil
关键词
Histoplasmosis; Leishmaniasis; Dogs; Immunodiffusion; DIAGNOSIS; REGION; STATE;
D O I
10.1016/j.actatropica.2011.05.007
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Histoplasmosis is a systemic infection caused by the fungus Histoplasma capsulatum. Environmental sources of infection for humans and animals in certain regions and the prevalence of infection in animals are frequently unknown. Because of the clinical and epidemiological similarities between histoplasmosis and leishmaniasis in northeastern Brazil, we decided to investigate the serologic evidence of H. capsulatum in dogs, considering that these animals can act as sentinels for histoplasmosis. A total of 224 serum samples from dogs were tested for antibodies against H. capsulatum through immunodiffusion. A total of 128(57.14%) samples were positive for leishmaniasis by indirect immunofluorescence assay and four (1.78%) samples were positive for antibodies against H. capsulatum. Immunological evidence of the co-existence of histoplasmosis and leishmaniasis in dogs living in urban areas was observed. Diagnosis and clinical management of these diseases in endemic areas should be improved by veterinarians. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码:203 / 205
页数:3
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