Secondary thyroid papillary carcinoma in osteosarcoma patients: Report of two cases

被引：4

作者：

Kim, Min Suk ^{[2
]}

Sim, Yoon Sang ^{[3
]}

Lee, Soo-Yong ^{[1
]}

Jeon, Dae-Geun ^{[1
]}

机构：

[1] Korea Canc Ctr Hosp, Dept Orthoped Surg, Seoul 139706, South Korea

[2] Korea Canc Ctr Hosp, Dept Pathol, Seoul 139706, South Korea

[3] Korea Canc Ctr Hosp, Dept Otolaryngol Head & Neck Surg, Seoul 139706, South Korea

来源：

JOURNAL OF KOREAN MEDICAL SCIENCE | 2008年 / 23卷 / 01期

关键词：

osteosarcoma; thyroid neoplasms; neoplasms; second primary;

D O I：

10.3346/jkms.2008.23.1.149

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report two cases of papillary thyroid carcinoma occurring after the successful treatment of osteosarcoma. One of the patients was administered with several alkylating agents and topoisomerase 11 inhibitor as part of the primary treatment of osteosarcoma. The onset of thyroid carcinoma occurred after 5 and 12 yr after cessation of the osteosarcoma therapy. All the patients involved in this study are alive and free of their malignancies. There have been eight case reports of these two malignancies occurring in the same patient. Thyroid carcinoma rarely occurs in patients with osteosarcoma; however, vigilant surveillance and long-term follow-up should be emphasized for all survivors.

引用

页码：149 / 152

页数：4

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