Identifying target groups for the prevention of depression in early adolescence: The TRAILS study

被引:12
作者
Monshouwer, Karin [1 ,2 ]
Smit, Filip [1 ,3 ]
Ruiter, Marijke [1 ]
Ormel, Hans [4 ]
Verhulst, Frank [5 ]
Vollebergh, Wilma [2 ]
Oldehinkel, Tineke [4 ]
机构
[1] Netherlands Inst Mental Hlth & Addict, Trimbos Inst, NL-3500 VJ Utrecht, Netherlands
[2] Univ Utrecht, Interdisciplinary Social Sci, Utrecht, Netherlands
[3] Vrije Univ Amsterdam Med Ctr, Dept Epidemiol & Biostat, EMGO, Inst Hlth & Hlth Care Res, Amsterdam, Netherlands
[4] Univ Groningen, Univ Med Ctr Groningen, Dept Psychiat, Interdisciplinary Ctr Psychiat Epidemiol, Groningen, Netherlands
[5] Erasmus MC, Dept Child & Adolescent Psychiat, Rotterdam, Netherlands
基金
英国医学研究理事会;
关键词
Early adolescence; Depression; CIDI; Prevention; Target groups; WORLD-HEALTH-ORGANIZATION; MENTAL-HEALTH; DISORDERS; SYMPTOMS; CHILDREN; VERSION; OVERWEIGHT; CHILDHOOD; OUTCOMES; SAMPLE;
D O I
10.1016/j.jad.2012.01.026
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background: Depression in adolescence is associated with long-term adverse consequences. The aim of the present study is to identify target groups at increased risk of developing depression in early adolescence, such that prevention is associated with the largest health benefit at population-level for the least effort. Methods: The analyses were conducted on data of the first (age range 10-12) and fourth (age range 17-20) wave of a population-based cohort study (N = 1538). The Composite International Diagnostic Interview (CIDI) was used to assess onset of major depression in early adolescence. High-risk groups were identified using exposure rate, incidence rate and population attributable fraction. Results: Prevention of depression onset in early adolescence is best targeted at children with one of the following risk profiles: a high body mass index in combination with (1) maternal depression (2) female gender, and (3) parental emotional rejection. Limitations: Age of onset of depression was assessed retrospectively. Conclusions: Only a few risk indicators are needed to identify a relatively small group which accounts for a substantial percentage of the new cases of depression in early adolescence. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:287 / 294
页数:8
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