A potential role for olanzapine in the treatment of hyperemesis gravidarum

被引：4
作者：
Sharma, Verinder [1 ,2 ,3 ]
Sharma, Sapna [4 ]
Hutson, Janine [2 ]
Martin, Alex [5 ]
机构：
[1] Univ Western Ontario, Dept Psychiat, London, ON, Canada
[2] Univ Western Ontario, Dept Obstet & Gynecol, London, ON, Canada
[3] St Josephs Hlth Care, Parkwood Inst Mental Hlth, London, ON, Canada
[4] McMaster Univ, Dept Obstet & Gynecol, Hamilton, ON, Canada
[5] Univ Calgary, PGY 1 Family Med, Calgary, AB, Canada
来源：
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | 2022年 / 35卷 / 25期
关键词：
Pregnancy; nausea; vomiting; hyperemesis gravidarum; treatment; olanzapine; safety; PREGNANCY; RISK;
D O I：
10.1080/14767058.2022.2046730
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Hyperemesis gravidarum is a rare but potentially serious complication of pregnancy. Some women with severe symptoms and possibly psychiatric comorbidities remain symptomatic despite the use of currently available treatments. Due to its favorable safety profile, antiemetic efficacy in other conditions, and 5-HT3 antagonism, olanzapine may be a potentially useful addition to the armamentarium for management of hyperemesis gravidarum resistant to standard- of-care treatment.
引用
收藏
页码：9532 / 9535
页数：4
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