Immediate renal tumor involution after radiofrequency thermal ablation

被引:31
作者
Ganguli, Suvranu [1 ]
Brennan, Darren D.
Faintuch, Salomao
Rayan, Mostafa E.
Goldberg, S. Nahum
机构
[1] Beth Israel Deaconess Med Ctr, Dept Radiol, Boston, MA 02215 USA
关键词
D O I
10.1016/j.jvir.2007.10.024
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
PURPOSE: To retrospectively evaluate solid renal tumor sizes before and after treatment with radiofrequency (RF) thermal ablation to assess for immediate changes on cross-sectional imaging. MATERIALS AND METHODS: Medical records were retrospectively reviewed in consecutive patients who underwent percutaneous image-guided RF thermal ablation for solid renal tumors between December 12, 2000, and December 13, 2006. All patients underwent noncontrast computed tomography (CT) immediately before and after RF ablation. Maximum renal tumor diameters were measured before and after ablation. Statistical analysis of tumor sizes before and after ablation and change in tumor sizes was performed with the paired Student t test with confidence intervals calculated. RESULTS: Seventy-two renal tumors were treated with RF ablation in 66 patients (42 men, 24 women; mean age, 68.4 years; range, 25-88 y). Mean tumor sizes were 27.5 mm (range, 9.8-64.8 mm; 95% Cl, 24.9-30.1 mm) before ablation and 22.1 mm (range, 5.3-67.3 mm; 95% CI, 19.4-24.8 mm) immediately after ablation. An average decrease in renal tumor size of 21% (range, -10% to 50%) was identified, with a mean tumor diameter decrease of 5.4 mm (P <.05; 95% Cl, 4.4-6.4 mm). No relationship between size or location of tumors and percentage decrease in size after RF ablation was identified. Measurement of tumors on 1-month follow-up CT showed no appreciable change compared with immediate postprocedural measurements. CONCLUSIONS: Renal tumors decrease in size immediately after treatment with RF thermal ablation. Immediate tumor involution after RF ablation should be anticipated and follow-up imaging studies should ideally be compared to a baseline tumor size measured as soon as possible after ablation.
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收藏
页码:412 / 418
页数:7
相关论文
共 26 条
[1]  
*AM CANC SOC, 2006, EST NEW CANC CAS DEA
[2]   SMALL RENAL PARENCHYMAL NEOPLASMS - FURTHER OBSERVATIONS ON GROWTH [J].
BOSNIAK, MA ;
BIRNBAUM, BA ;
KRINSKY, GA ;
WAISMAN, J .
RADIOLOGY, 1995, 197 (03) :589-597
[3]   Concepts, considerations, and concerns on the cutting edge of radiofrequency ablation [J].
Brown, DB .
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2005, 16 (05) :597-613
[4]   Laparoscopic cryoablation of solid renal masses: Intermediate term followup [J].
Cestari, A ;
Guazzoni, G ;
Dell'Acqua, V ;
Nava, L ;
Cardone, G ;
Balconi, G ;
Naspro, R ;
Montorsi, F ;
Rigatti, A .
JOURNAL OF UROLOGY, 2004, 172 (04) :1267-1270
[5]   Reporting standards for percutaneous thermal ablation of renal cell carcinoma [J].
Clark, Timothy W. I. ;
Millward, Steven F. ;
Gervais, Debra A. ;
Goldberg, S. Nahum ;
Grassi, Clement J. ;
Kinney, Thomas B. ;
Phillips, David A. ;
Sacks, David ;
Cardella, John F. .
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2006, 17 (10) :1563-1570
[6]   Prospective analysis of computerized tomography and needle biopsy with permanent sectioning to determine the nature of solid renal masses in adults [J].
Dechet, CB ;
Zincke, H ;
Sebo, TJ ;
King, BF ;
LeRoy, AJ ;
Farrow, GM ;
Blute, ML .
JOURNAL OF UROLOGY, 2003, 169 (01) :71-74
[7]   Imaging-guided radiofrequency ablation of solid renal tumors [J].
Farrell, MA ;
Charboneau, WJ ;
DiMarco, DS ;
Chow, GK ;
Zincke, H ;
Callstrom, MR ;
Lewis, BD ;
Lee, RA ;
Reading, CC .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2003, 180 (06) :1509-1513
[8]   Long-term results of nephron sparing surgery for localized renal cell carcinoma: 10-year followup [J].
Fergany, AF ;
Hafez, KS ;
Novick, AC .
JOURNAL OF UROLOGY, 2000, 163 (02) :442-445
[9]   Radio-frequency ablation of renal cell carcinoma: Early clinical experience [J].
Gervais, DA ;
McGovern, FJ ;
Wood, BJ ;
Goldberg, SN ;
McDougal, WS ;
Mueller, PR .
RADIOLOGY, 2000, 217 (03) :665-672
[10]   Renal cell carcinoma: Clinical experience and technical success with radio-frequency ablation of 42 tumors [J].
Gervais, DA ;
McGovern, F ;
Arellano, RS ;
McDougal, WS ;
Mueller, PR .
RADIOLOGY, 2003, 226 (02) :417-424