Thrombotic Microangiopathy Presenting with a Considerable Accumulation of Ascites: A Case Report

被引：1

作者：

Shirai, Tsuyoshi ^{[1
]}

Ishii, Tomonori ^{[1
]}

Watanabe, Ryu ^{[1
]}

Tajima, Yumi ^{[1
]}

Fujii, Hiroshi ^{[1
]}

Takasawa, Naruhiko ^{[1
]}

Sato, Hiroshi ^{[2
]}

Harigae, Hideo ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Med, Dept Hematol & Rheumatol, Sendai, Miyagi 980, Japan

[2] Tohoku Univ, Grad Sch Med, Dept Nephrol Hypertens & Endocrinol, Sendai, Miyagi 980, Japan

来源：

INTERNAL MEDICINE | 2011年 / 50卷 / 01期

关键词：

ascites; renal biopsy; thrombocytopenia; thrombotic microangiopathy; HEPATIC VENOOCCLUSIVE DISEASE; HEMOLYTIC-UREMIC SYNDROME; THROMBOCYTOPENIC PURPURA;

D O I：

10.2169/internalmedicine.50.4330

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 46-year-old man presented with fever, thrombocytopenia, and a considerable accumulation of ascites. Although prednisolone and intravenous cyclophosphamide pulse (IVCY) were effective, he experienced recurrence. Renal insufficiency and hemolytic anemia developed subsequently. Schistocytes, negative Coombs' test, and elevated lactate dehydrogenase levels indicated thrombotic microangiopathy (TMA). He recovered well after receiving plasma infusion, IVCY, and prednisolone. Renal biopsy revealed subendothelial widening, thereby confirming TMA. This is a very rare case of TMA that presented with a considerable volume of ascites.

引用

页码：53 / 57

页数：5

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