Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia

被引：62

作者：

Gupta, Aditya K. ^{[1
,2
]}

Cole, John ^{[3
]}

Deutsch, David P. ^{[1
,4
]}

Everts, Peter A. ^{[5
]}

Niedbalski, Robert P. ^{[1
,6
]}

Panchaprateep, Ratchathorn ^{[1
,7
]}

Rinaldi, Fabio ^{[1
,8
]}

Rose, Paul T. ^{[1
,9
]}

Sinclair, Rodney ^{[10
]}

Vogel, James E. ^{[1
,11
,12
]}

Welter, Ryan J. ^{[13
]}

Zufelt, Michael D. ^{[1
,14
]}

Puig, Carlos J. ^{[1
,15
]}

机构：

[1] Univ Toronto, ISHRS, Ad Hoc Comm PRP, Sch Med, Toronto, ON, Canada

[2] Univ Toronto, Dept Med, Div Dermatol, Sch Med, Toronto, ON, Canada

[3] Cole Hair Transplant Grp, Alpharetta, GA USA

[4] Bosley Med, Beverly Hills, CA USA

[5] EmCyte Corp, Ft Myers, FL USA

[6] Northwest Hair Restorat, Tacoma, WA USA

[7] Chulalongkorn Univ, King Chulalongkorn Mem Hosp, Fac Med, Div Dermatol,Dept Med, Bangkok, Thailand

[8] Int Hair Res Fdn, Milan, Italy

[9] Hair Transplant Inst Miami, Coral Gables, FL USA

[10] Sinclair Dermatol, Melbourne, Vic, Australia

[11] Johns Hopkins Univ Hosp, Dept Surg, Div Plast Surg, Baltimore, MD 21287 USA

[12] Sch Med, Baltimore, MD 21287 USA

[13] New England Ctr Hair Restorat, Westwood, MA USA

[14] Hair Restorat Ctr Utah, Salt Lake City, UT USA

[15] Phys Hair Restorat Ctr, Houston, TX USA

来源：

DERMATOLOGIC SURGERY | 2019年 / 45卷 / 10期

关键词：

PATTERN HAIR LOSS; GROWTH-FACTORS; DOUBLE-BLIND; EFFICACY;

D O I：

10.1097/DSS.0000000000001894

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

BACKGROUND Platelet-rich plasma (PRP) treatment may encourage hair growth by promoting cellular maturation, differentiation, and proliferation. OBJECTIVE The objective of this study was to evaluate the effectiveness of PRP as a treatment for androgenetic alopecia (AGA). MATERIALS AND METHODS A literature search combined with meta-analysis was used to calculate the overall standardized mean difference (SMD) in hair density in patients treated with PRP injections in comparison with baseline and placebo treatment. Chi squared analysis and Fisher exact test were used to investigate variation in protocols. RESULTS The overall SMD in hair density was 0.58 (95% confidence interval [CI]: 0.35-0.80) and 0.51 (95% CI: 0.23-0.80, p < .0004) in favor of PRP treatment when compared with baseline and placebo treatment, respectively. CONCLUSION Platelet-rich plasma is beneficial in the treatment of AGA. It is recommended that 3 monthly sessions of PRP (once monthly x3 treatments) be used followed by a 3- to 6-month maintenance period.

引用

页码：1262 / 1273

页数：12

共 65 条

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