Twisting and stretching single DNA molecules

被引：265
|
作者：
Strick, T
Allemand, JF
Croquette, V
Bensimon, D
机构：
[1] ENS, UMR 8550 CNRS, LPS, F-75231 Paris 05, France
[2] ENS, UMR 8640 CNRS, Dept Chim, F-75231 Paris 05, France
来源：
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY | 2000年 / 74卷 / 1-2期
关键词：
D O I：
10.1016/S0079-6107(00)00018-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The elastic properties of DNA are essential for its biological function. They control its bending and twisting as well as the induction of structural modifications in the molecule. These call affect its interaction with the cell machinery. The response of a single DNA molecule to a mechanical stress can be precisely determined in single-molecule experiments which give access to an accurate measurement of the elastic parameters of DNA. (C) 2000 Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：115 / 140
页数：26
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