xQTL workbench: a scalable web environment for multi-level QTL analysis

被引：11

作者：

Arends, Danny ^{[1
]}

van der Velde, K. Joeri ^{[1
]}

Prins, Pjotr ^{[1
,2
]}

Broman, Karl W. ^{[3
]}

Moller, Steffen ^{[4
]}

Jansen, Ritsert C. ^{[1
]}

Swertz, Morris A. ^{[1
,5
,6
]}

机构：

[1] Univ Groningen, Groningen Bioinformat Ctr, Groningen, Netherlands

[2] Wageningen Univ, Nematol Lab, Wageningen, Netherlands

[3] Univ Wisconsin, Dept Biostat & Med Informat, Madison, WI USA

[4] Univ Lubeck, Inst Neuro & Bioinformat, Lubeck, Germany

[5] Univ Groningen, Genom Coordinat Ctr, Univ Med Ctr Groningen, NL-9700 AB Groningen, Netherlands

[6] European Bioinformat Inst, EMBL EBI, Hinxton, England

来源：

BIOINFORMATICS | 2012年 / 28卷 / 07期

基金：

美国国家卫生研究院;

关键词：

EXPERIMENTAL CROSSES; MOLGENIS; R/QTL;

D O I：

10.1093/bioinformatics/bts049

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

xQTL workbench is a scalable web platform for the mapping of quantitative trait loci (QTLs) at multiple levels: for example gene expression (eQTL), protein abundance (pQTL), metabolite abundance (mQTL) and phenotype (phQTL) data. Popular QTL mapping methods for model organism and human populations are accessible via the web user interface. Large calculations scale easily on to multi-core computers, clusters and Cloud. All data involved can be uploaded and queried online: markers, genotypes, microarrays, NGS, LC-MS, GC-MS, NMR, etc. When new data types come available, xQTL workbench is quickly customized using the Molgenis software generator.

引用

页码：1042 / 1044

页数：3

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