Immune reconstitution inflammatory syndrome associated with disseminated histoplasmosis and TNF-alpha inhibition

被引：10

作者：

Wright, Theodore ^{[1
]}

Coruh, Basak ^{[2
]}

Fredricks, David ^{[3
]}

Kim, Nina ^{[1
]}

机构：

[1] Univ Washington, Harborview Med Ctr, Div Infect Dis, Seattle, WA 98104 USA

[2] Univ Washington, Med Ctr, Div Pulm & Crit Care, Seattle, WA 98104 USA

[3] Univ Washington, Fred Hutchinson Canc Res Ctr, Div Infect Dis, Seattle, WA 98104 USA

来源：

MEDICAL MYCOLOGY CASE REPORTS | 2019年 / 23卷

关键词：

Immune reconstitution inflammatory syndrome; Histoplasmosis; TNF-alpha; TUMOR-NECROSIS-FACTOR; INFLIXIMAB; MYCOBACTERIAL; INFECTIONS; BLOCKADE; THERAPY;

D O I：

10.1016/j.mmcr.2018.12.008

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Endemic fungal infections are a significant problem for patients on TNF-alpha inhibitors. Immune reconstitution inflammatory syndrome, IRIS, can present in patients with waning TNF-alpha inhibition and an endemic fungal infection. There may be a potential role that TNF-alpha inhibitors can play in mitigating IRIS related to disseminated endemic fungal infections.

引用

页码：62 / 64

页数：3

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