Immune reconstitution inflammatory syndrome associated with disseminated histoplasmosis and TNF-alpha inhibition

被引：10
作者：
Wright, Theodore [1 ]
Coruh, Basak [2 ]
Fredricks, David [3 ]
Kim, Nina [1 ]
机构：
[1] Univ Washington, Harborview Med Ctr, Div Infect Dis, Seattle, WA 98104 USA
[2] Univ Washington, Med Ctr, Div Pulm & Crit Care, Seattle, WA 98104 USA
[3] Univ Washington, Fred Hutchinson Canc Res Ctr, Div Infect Dis, Seattle, WA 98104 USA
来源：
MEDICAL MYCOLOGY CASE REPORTS | 2019年 / 23卷
关键词：
Immune reconstitution inflammatory syndrome; Histoplasmosis; TNF-alpha; TUMOR-NECROSIS-FACTOR; INFLIXIMAB; MYCOBACTERIAL; INFECTIONS; BLOCKADE; THERAPY;
D O I：
10.1016/j.mmcr.2018.12.008
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Endemic fungal infections are a significant problem for patients on TNF-alpha inhibitors. Immune reconstitution inflammatory syndrome, IRIS, can present in patients with waning TNF-alpha inhibition and an endemic fungal infection. There may be a potential role that TNF-alpha inhibitors can play in mitigating IRIS related to disseminated endemic fungal infections.
引用
收藏
页码：62 / 64
页数：3
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