Brave new epigenomes: the dawn of epigenetic engineering

被引：13

作者：

Koeeferle, Anna ^{[1
]}

Stricker, Stefan H. ^{[2
,3
]}

Beck, Stephan ^{[1
]}

机构：

[1] UCL, Inst Canc, Med Genom, London WC1E 6BT, England

[2] German Res Ctr Environm Hlth, Helmholtz Zentrum, Inst Stem Cell Res, Funct Epigenet, D-85764 Neuherberg, Germany

[3] Univ Munich, Biomed Ctr, D-82152 Planegg Martinsried, Germany

来源：

GENOME MEDICINE | 2015年 / 7卷

基金：

英国惠康基金;

关键词：

GENES;

D O I：

10.1186/s13073-015-0185-8

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

New methods for epigenome editing now make it possible to manipulate the epigenome in living cells with unprecedented specificity and efficiency. These ground-breaking approaches are beginning to yield novel insights into the function of individual chromatin marks in the context of cellular phenotype.

引用

页数：3

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