Molecular genetics related to non-Hodgkin lymphoma

被引：0

作者：

Guo, Ming ^{[1
]}

Mao, Xianglin ^{[1
]}

Ding, Xiaoqing ^{[1
]}

机构：

[1] Beijing Univ Tradit Chinese Med, Affiliated Hosp 2, Dept Hematol, Beijing 100078, Peoples R China

来源：

OPEN LIFE SCIENCES | 2016年 / 11卷 / 01期

关键词：

Non-Hodgkin lymphoma; Molecular genetics; B-CELL LYMPHOMA; CHROMOSOME-ABNORMALITIES; LYMPHOBLASTIC LYMPHOMA; EXPRESSION; PATHOGENESIS; ADOLESCENTS; MICRORNAS; CHILDREN; CHILDHOOD; MUTATIONS;

D O I：

10.1515/biol-2016-0011

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Non-Hodgkin lymphoma (NHL) is a serious disease, with a high proportion of mortality. Molecular genetic abnormalities are very common in NHL, but specific characterization in accordance to molecular genetics for lymphoma subtypes is not yet completed. This article summarizes the relationship between B-and T-NHL and molecular genetics. We focus on NHL subtypes and emphasize its features to figure out what is exposed about NHL genetics. The basis of this method is collection of biological specimens for genomic and genetic analyses. This summary may help to prompt prediction of outcomes and guide therapy in the future.

引用

页码：86 / 90

页数：5

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