Zirconocene-assisted remote cleavage of C-C and C-O bonds: application to acyclic stereodefined metalated hydrocarbons

被引：15
作者：
Bruffaerts, J.
Pierrot, D.
Marek, I. [1 ]
机构：
[1] Technion Israel Inst Technol, Schulich Fac Chem, Mallat Family Lab Organ Chem, IL-32000 Haifa, Israel
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2016年 / 14卷 / 44期
基金：
欧洲研究理事会;
关键词：
CATALYZED ASYMMETRIC ISOMERIZATION; QUATERNARY STEREOGENIC CENTERS; HECK ARYLATIONS; FUNCTIONALIZATION; DERIVATIVES; ALKENES; DIENES; ALKYLIDENECYCLOPROPANES; COMPLEXES; STRATEGY;
D O I：
10.1039/c6ob01910b
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The molding of molecules through remote functionalisation has increasingly become popular as it provides original and flexible synthetic alternatives to classical retrosynthetic analysis. In this Perspective article, we summarise more than a decade of studies in the specific field of remote activation of inert C-C and C-O bonds using the unique abilities of organozirconocene species mainly from our own research group. By demonstrating that these reactions represent novel and powerful entries towards acyclic stereodefined reactive organometallic species, we aim to show the vast opportunities this concept-driven methodology discovery offers.
引用
收藏
页码：10325 / 10330
页数：6
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