Reviewing Mimosoideae lectins: A group of under explored legume lectins

被引：19

作者：

Cavada, Benildo Sousa ^{[1
]}

Silva Osterne, Vinicius Jose ^{[1
]}

Oliveira, Messias Vital ^{[1
]}

Pinto-Junior, Vanir Reis ^{[2
]}

Lima Silva, Mayara Torquato ^{[3
]}

Bari, Alfa Umaro ^{[1
]}

Lima, Lara Dias ^{[1
]}

Lossio, Claudia Figueiredo ^{[1
]}

Nascimento, Kyria Santiago ^{[1
]}

机构：

[1] Univ Fed Ceara, Dept Bioquim & Biol Mol, Fortaleza, Ceara, Brazil

[2] Univ Fed Ceara, Dept Fis, Fortaleza, Ceara, Brazil

[3] Univ Fed Santa Catarina, Dept Bioquim, Florianopolis, SC, Brazil

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2020年 / 154卷

关键词：

Lectins; Mimosoideae; Leguminosae; ACACIA-FARNESIANA SEEDS; CHITIN-BINDING PROTEIN; PARKIA-PLATYCEPHALA; CARBOHYDRATE-BINDING; CANAVALIA-MARITIMA; CRYSTAL-STRUCTURE; PURIFICATION; BIGLOBOSA; REVEALS; TOOLS;

D O I：

10.1016/j.ijbiomac.2020.03.113

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Lectins are proteins capable of specific and reversible binding to mono- and/or oligosaccharides, and within this group, Legume lectins are the most studied. However, most of these studies focus on the Papilionoideae subfamily, with Caesalpinioideae and Mimosoideae lectins being significantly less explored in the literature. The Mimosoideae subfamily consists of at least 79 genera and 3275 species, but, to date, only about 14 lectins have been purified, a fact which shows the lack of studies for this group. Based on their purification protocols, as well as physicochemical and structural properties, Mimosoideae lectins are very heterogeneous. Despite the few studies, a wide variety of biological activities have been tested, including, for example, inflammatory, anticancer, antibacterial, and antifungal. In this context, the present review aims to summarize the available data regarding the purification, physicochemical and structural properties, as well as biological activities, of lectins extracted from plants of the Mimosoideae subfamily in order to bring more insight to researchers interested in further exploring the potential of these molecules. (C) 2020 Elsevier B.V. All rights reserved.

引用

页码：159 / 165

页数：7

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